41877-16-1

Upstream product

• 875-59-2 4'-hydroxy-2'methylacetophenone 

Downstream Products

• 1265683-74-6 2-(4-hydroxy-2-methylphenyl)-2-oxoethyl methanesulfonate 
• 78326-88-2 5-benzyloxy-1-indanone 
• 22574-58-9 4-hydroxymethyl-3-methylphenol 
• 29336-53-6 4-hydroxy-2-methylphenylacetic acid 
• 114474-04-3 4-hydroxy-2-methylphenylacetic acid methyl ester 
• 1265683-75-7 2-(4-hydroxy-2-methylphenyl)-2-oxoethyl acetate 
• 1265683-76-8 2-(4-hydroxy-2-methylphenyl)-2-oxoethyl formate 
• 1192215-83-0 8-bromo-3,7-dihydro-3-methyl-7-[2-(2-methyl-4-hydroxyphenyl)-2-oxoethyl]-1H-purine-2,6-dione 
• 252561-71-0 3-Methyl₄-(1,3-thiazol-4-yl)phenol 
• 578-39-2 4-hydroxy-2-methylbenzoic acid 

Relevant academic research and scientific papers

Supramolecular Storage and Controlled Photorelease of an Oxidizing Agent using a Bambusuril Macrocycle

The oxidizing ability of peroxodisulfate upon complexation inside the Bambusuril macrocycle cavity is inhibited. This dianionic agent can be released on demand from its stable 1:1 complex in water (log Ka=6.9 m?1) by addition of a more strongly bound anion, such as iodide (log Ka=7.1 m?1), which can also be delivered in situ upon irradiation from a 4-hydroxyphenacyl iodide derivative with spatial and temporal precision. The oxidizing properties of peroxodisulfate ions liberated from the complex recover and can take part in subsequent chemical transformations.

The power of solvent in altering the course of photorearrangements

A clean bifurcation between two important photochemical reactions through competition of a triplet state Type II H-abstraction reaction with a photo-Favorskii rearrangement for (o/p)-hydroxy-o-methylphenacyl esters that depends on the water content of the solvent has been established. The switch from the anhydrous Type II pathway that yields indanones to the aqueous-dependent pathway producing benzofuranones occurs abruptly at low water concentrations (～8%). The surprisingly clean yields suggest that such reactions are synthetically promising.

Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same

Benzothiophenes and related compounds of formula (1), wherein A, B, Z are independently —CH═, —CR4═ or ═N—; X is —S—, —O—, —NH—, —NR2, —CH2—CH2—, CH2—CH2—CH2—, —CH2—O—; —OCH2—, —CH2—S—, —CO—, —SCH2—. —N═CR2— or —R2C═N—; Y is optionally substituted phenyl, alkyl, cycloalkyl, cycloalkenyl, heterocycle or bicyclic ring system; D is —CO—, CR2R3—, —CONH—, —NHCO—, —CR2(OH)—, —CONR2, NOR1 CH—NO2 N—CN —NR2—CO—, —C—, —C—, —C—; E is a single bond, optionally substituted phenyl, heterocycle; Z1 is —(CH2)p W(CH2)q—, —O(CH2)p CR5R6— or —O(CH2)p W(CH2)q; G is —NR7R8, (a), (b), (c), a 5- or 6-membered saturated, unsaturated or partially unsaturated and optionally substituted heterocycle or a bicyclic amine containing 5 to 12 carbon atoms either bridged or fused and optionally substituted and R is halogen, —NR2R3, —NHCOR2, —NHSO2R2, —CR2R3OH, —CONR2R3, —SO2NR2R3, OH, —OR1, —O—COR1; are estrogen agonists which are useful for treating syndromes and diseases caused by estrogen deficiency.