41878-51-7

Basic information

• Product Name: 3-Chloro-4-hydroxy-1-Methylquinolin-2(1H)-one
• Synonyms: 3-Chloro-4-hydroxy-1-Methylquinolin-2(1H)-one
• CAS NO: 41878-51-7
• Molecular Formula: C₁₀H₈ClNO₂
• Molecular Weight: 209.62902
• Mol File: 41878-51-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 280.4°C at 760 mmHg
• Flash Point: 123.4°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 0.00181mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Chloro-4-hydroxy-1-Methylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4-hydroxy-1-Methylquinolin-2(1H)-one(41878-51-7)
• EPA Substance Registry System: 3-Chloro-4-hydroxy-1-Methylquinolin-2(1H)-one(41878-51-7)

Safety Data

• Hazardous Substances Data: 41878-51-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H8ClNO2/c1-12-7-5-3-2-4-6(7)9(13)8(11)10(12)14/h2-5,14H,1H3

Upstream product

• 1677-46-9 4-hydroxy-1-methyl-2(1H)-quinolone 
• 36949-55-0 4-hydroxy-1-methyl-3-nitro-2-(1H)quinolinone 
• 68903-69-5 1-methyl-3-(phenyl-λ³-iodanylidene)quinoline-2,4(1H,3H)-dione 

Downstream Products

• 531502-88-2 4-chloro-1-methyl-3-phenylsulfonylquinolin-2(1H)-one 
• 531502-91-7 4-azido-1-methyl-3-phenylsulfanylquinolin-2(1H)-one 
• 380633-14-7 4-chloro-1-methyl-3-phenylsulfanylquinolin-2(1H)-one 
• 69380-18-3 1,2-Dihydro-4-hydroxy-1-methyl-3-phenylsulfonyl-2-chinolon 
• 69146-80-1 4-hydroxy-1-methyl-3-phenylsulfinylquinolin-2(1H)-one 
• 18693-13-5 4-hydroxy-1-methyl-3-phenylsulfanylquinolin-2(1H)-one 

Relevant articles and documents

Manganese(III) acetate mediated radical reactions leading to araliopsine and related quinoline alkaloids

Tricyclic quinoline alkaloids, including araliopsine 2, can be prepared in 'one-pot' by reaction of 4-hydroxy-1-methyl-2(1H)-quinoline 5 or 2,4-quinolinediol 31 with manganese(III) acetate in the presence of a variety of electron-rich alkenes. The reaction mechanism involves an initial intermolecular radical addition reaction followed by radical oxidation and cyclisation steps. Both angular and linear tricyclic alkaloids can be formed and the regioselectivity of the cyclisation is shown to depend on whether alkyl or aryl groups are attached to the alkene.

SPIROCYCLIC MEISENHEIMER COMPLEXES. XXXV. POSSIBLE FORMATION OF ANIONIC SPIRO ? COMPLEXES IN THE 3-NITRO-2(1H)-QUINOLINONE SYSTEM

The reaction of 1-methyl-3-nitro- and 1-methyl-3,6-dinitro-4-chloro-2(1H)-quinolinones with 1,2-ethanedithiol leads to 1-methyl-3-nitro- and 1-methyl-3,6-dinitrospirodithiolanes>.The ability of the latter to form anionic Meisenheimer spiro ? complexes is less than in the analogous derivatives of benzopyranone and benzothiopyranone.