18693-13-5

Basic information

• Product Name: 3-(cyclohexylsulfanyl)-2-hydroxy-1-methylquinolin-4(1H)-one
• CAS NO: 18693-13-5
• Molecular Formula: C₁₆H₁₃NO₂S
• Molecular Weight: 289.3926
• Mol File: 18693-13-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 406°C at 760 mmHg
• Flash Point: 199.3°C
• Density: 1.28g/cm³
• Vapor Pressure: 2.56E-07mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 3-(cyclohexylsulfanyl)-2-hydroxy-1-methylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(cyclohexylsulfanyl)-2-hydroxy-1-methylquinolin-4(1H)-one(18693-13-5)
• EPA Substance Registry System: 3-(cyclohexylsulfanyl)-2-hydroxy-1-methylquinolin-4(1H)-one(18693-13-5)

Safety Data

• Hazardous Substances Data: 18693-13-5(Hazardous Substances Data)

Upstream product

• 1677-46-9 4-hydroxy-1-methyl-2(1H)-quinolone 
• 882-33-7 diphenyldisulfane 
• 591-50-4 iodobenzene 
• 108-98-5 thiophenol 
• 98-09-9 benzenesulfonyl chloride 
• 80-17-1 benzenesufonyl hydrazide 
• 41878-51-7 4-hydroxy-1-methyl-3-chloro-2(1H)-quinolinone 

Downstream Products

• 531502-88-2 4-chloro-1-methyl-3-phenylsulfonylquinolin-2(1H)-one 
• 531502-91-7 4-azido-1-methyl-3-phenylsulfanylquinolin-2(1H)-one 
• 380633-14-7 4-chloro-1-methyl-3-phenylsulfanylquinolin-2(1H)-one 
• 69380-18-3 1,2-Dihydro-4-hydroxy-1-methyl-3-phenylsulfonyl-2-chinolon 
• 69146-80-1 4-hydroxy-1-methyl-3-phenylsulfinylquinolin-2(1H)-one 

Relevant articles and documents

Copper-Mediated Direct Sulfenylation of 4-Hydroxyquinolinones and 4-Hydroxypyridones with Aryl Thiols via a C-H Functionalization Process

An efficient approach for the direct sulfanylation of 4-hydroxyquinolinones and 4-hydroxypyridones with aryl thiols in the presence of CuI/DMSO has been developed. The substrate scope is broad, allowing facile synthesis of a range of structurally diverse 3-sulfanyl-4-hydroxyquinolinones and 3-sulfanyl-4-hydroxypyridones in good efficiency.

Novel Method for Preparing 4-hydroxy-3-sulfanylcoumarin Derivatives or 4-hydroxy-3-sulfanylquinoline Derivatives and Their Compounds Made Thereby, and Its Use

The present invention relates to 4-hydroxy-3-sulfanylcoumarin derivatives represented by chemical formula 1, 4-hydroxy-3-sulfanylquinolinone derivatives represented by chemical formula 2, novel preparation methods thereof, and uses thereof. According to the present invention, the preparation methods can reduce the preparation cost by utilizing inexpensive catalysts, and at the same time, can yield desired products with high yield. In the chemical formula 1, R_1 to R_4 are as described in the present invention. In the chemical formula 2, R_5 to R_7 are as described in the present invention.COPYRIGHT KIPO 2018

Copper(I) Bromide-Dimethyl Sulfide-Catalyzed Direct Sulfanylation of 4-Hydroxycoumarins and 4-Hydroxyquinolinones with Arylsulfonylhydrazides and Selective Fluorescence Switch- On Sensing of Cadmium(II) Ion in Water

An efficient protocol for the direct sulfanylation of various 4-hydroxycoumarins and 4-hydroxyquinolinones in good yield with arylsulfonylhydrazides as sulfanylating agents was developed via copper(I) bromide?dimethyl sulfide-catalyzed S–O, S–N bond cleavage and C–S cross-coupling reactions. A highly selective fluorescence turning-on sensing of cadmium(II) ions in water using the synthesized 3-sulfanyl-4-hydroxycoumarin derivative was also investigated. (Figure presented.).