41879-99-6Relevant academic research and scientific papers
Umpolung Reaction of α-Imino Thioesters and the Subsequent C-C Bond Formation with the Unexpected Alkylthio Rearrangement
Mizota, Isao,Ueda, Chihiro,Tesong, Yun,Tsujimoto, Yusuke,Shimizu, Makoto
supporting information, p. 2291 - 2296 (2018/04/30)
An umpolung reaction of the α-imino thioester was examined, and we found that α-imino thioesters were more effective substrates for the umpolung N-alkylation than conventional α-imino esters and they gave N-alkylated amino thioesters in high yields under mild reaction conditions in a short time. A new type of C-C bond formation followed by an unexpected rearrangement of the alkylthio group took place with the unsaturated ketones to afford the β-alkylthio-α-amino thioesters in high yields with good diastereoselectivity.
On the thermal Pummerer rearrangement of substituted sulfoxides
Marzorati, Liliana,Yoshikawa, Eduardo K.C.,Braga, Ataualpa A.C.,Di Vitta, Claudio
, p. 248 - 260 (2014/04/03)
Sulfoxides bearing thioester and ester groups at the position under heating at ca. 140C undergo Pummerer thermal rearrangement. However, for sulfonyl sulfoxide, a complex mixture of products is formed. Plausible mechanism is advanced(equation presented. 2013
