41958-45-6Relevant academic research and scientific papers
Reaction of α,β-alkynylketones with β-amino alcohols: Pseudoephedrine- assisted cleavage of triple bond via formal internal redox process
Vasilevsky, Sergei F.,Davydova, Maria P.,Mamatuyk, Victor I.,Pleshkova, Nadezhda V.,Fadeev, Dmitry S.,Alabugin, Igor V.
, p. 377 - 379 (2015/10/19)
Reaction of 3-aryl-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-ones with (+)-pseudoephedrine leads to products of alkyne moiety cleavage, namely, 1-(3,4,5-trimethoxyphenyl)ethanone and N-(1-hydroxy-1-phenylprop-2-yl)-N-methylbenzamides. In the course of the process one of alkyne carbons undergoes a formal reduction to a Me group, whereas the other one is oxidized to a C(O)NRR' moiety.
