41997-33-5Relevant academic research and scientific papers
Silica Chloride: A Versatile Heterogeneous Catalyst for Esterification and Transesterification
Srinivas,Mahender,Das, Biswanath
, p. 2479 - 2482 (2007/10/03)
Silica chloride has been found to be an efficient catalyst for esterification of carboxylic acids (aliphatic, aromatic and conjugated) with alcohols (primary, secondary and tertiary) as well as for transesterification of esters (by both alcoholysis and acidolysis).
A highly convenient, efficient, and selective process for preparation of esters and amides from carboxylic acids using Fe3+-K-10 montmorillonite clay
Srinivas,Das, Biswanath
, p. 1165 - 1167 (2007/10/03)
In the presence of Fe3+-K-10 montmorillonite clay as a catalyst, aliphatic carboxylic acids selectively produced the corresponding esters in the presence of aromatic carboxylic acids by treatment with alcohols. Both the aliphatic and aromatic carboxylic acids formed the amides by reacting with the aliphatic amines, but only the aliphatic carboxylic acids yielded the anilides by treatment with aromatic amines. The catalyst is recoverable and recyclable.
A Simple and Efficient Selective Esterification of Aliphatic Carboxylic Acids in the Presence of Aromatic Carboxylic Acids
Das, Biswanath,Venkataiah, B.,Madhusudhan, P.
, p. 59 - 60 (2007/10/03)
Aliphatic carboxylic acids were esterificated selectively at room temperature in the presence of aromatic carboxylic acids by treatment with alcohols in the presence of silica gel supported NaHSO4 catalyst.
Transesterification of methyl arylacetates wtih lithium alkoxides
Bhawal,Khanapure,Biehl
, p. 112 - 114 (2007/10/02)
A series of methyl arylacetates were transesterified in excellent yields using lithium alkoxides derived from primary, secondary, and tertiary aliphatic alcohols, benzyl alcohols, and allyl alcohol.
Oxazolophanes as masked cyclopeptide alkaloid equivalents: Cyclic peptide chemistry without peptide couplings
Lipshutz, Bruce H.,Huff, Bret E.,McCarthy, Keith E.,Miller, Todd A.,Jaweed Mukarram,Siahaan, Teruna J.,Vaccaro, Wayne D.,Webb, Hugh,Falick, Arnold M.
, p. 7032 - 7041 (2007/10/02)
Synthetic studies on the preparation of heteroatom-substituted, novel [3.3]oxazolophanes as precursors to the 14-membered ring system characteristic of the cyclopeptide alkaloids are reported. Simpler model systems are discussed, as is the successful form
Ester Derivatives of 2,6-Bis(1-pyrrolidinylmethyl)-4-benzamidophenol as Short-Acting Antiarrhythmic Agents. 1
Stout, David M.,Black, Lawrence A.,Barcelon-Yang, Cynthia,Matier, W. L.,Brown, Barry S.,et al.
, p. 1910 - 1913 (2007/10/02)
In an effort to find a replacement for the iv antiarrhythmic drug lidocaine having reduced systemic and central nervous system effects, activity against supraventricular as well as ventricular arrhythmias, and a biological half-life of less than 15 min, derivatives of the orally active class Ic clinical agent 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol, 1 (ACC-9358), were synthesized and tested.Compounds with ester groups attached to the phenyl ring were either weakly active or toxic.Replacement of the formanilide function with alkyl esters afforded compounds with antiarrhythmic activity in the range of 1.When the ester carboxyl was separated from the bis(aminomethyl)phenol by methylene units, very short half-lives were observed in human blood.In general, these compounds also had low lipophilic character.
