420119-00-2

Upstream product

• 143961-89-1 Boc-Tyr(Cl₂-Bzl)-H 
• 420118-99-6 (E)-(S)-4-tert-Butoxycarbonylamino-5-[4-(2,6-dichloro-benzyloxy)-phenyl]-pent-2-enoic acid methyl ester 

Downstream Products

• 420118-91-8 {(2S,3S,6R)-6-Benzyl-3-[4-(2,6-dichloro-benzyloxy)-benzyl]-5-oxo-piperazin-2-yl}-acetic acid methyl ester 
• 420118-92-9 (E)-(S)-4-((R)-2-Amino-3-phenyl-propionylamino)-5-[4-(2,6-dichloro-benzyloxy)-phenyl]-pent-2-enoic acid methyl ester 
• 176755-26-3 (E)-(S)-4-((R)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-5-[4-(2,6-dichloro-benzyloxy)-phenyl]-pent-2-enoic acid methyl ester 

Relevant academic research and scientific papers

An efficient synthesis of the piperazinone fragment of pseudotheonamide A1 via a stereoselective intramolecular Michael ring closure

The stereoselective intramolecular Michael ring closure of the dipeptide efficiently gives the piperazinone fragment of pseudotheonamide A1, a serine protease inhibitor from the marine sponge Theonella swinhoei.