42048-11-3 Usage
General Description
2-Chloro-6-iodotoluene is a chemical compound with the molecular formula C7H6ClI. It is a halogenated aromatic compound that is used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is a white to light yellow crystalline solid with a molecular weight of 241.48 g/mol. 2-Chloro-6-iodotoluene is insoluble in water but soluble in organic solvents such as ether and benzene. It is a potentially hazardous chemical and should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. 2-Chloro-6-iodotoluene is commonly used in research and industrial applications as a building block in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 42048-11-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,0,4 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 42048-11:
(7*4)+(6*2)+(5*0)+(4*4)+(3*8)+(2*1)+(1*1)=83
83 % 10 = 3
So 42048-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClI/c1-5-6(8)3-2-4-7(5)9/h2-4H,1H3
42048-11-3Relevant articles and documents
N-Iodosuccinimide (NIS) in Direct Aromatic Iodination
Bergstr?m, Maria,Suresh, Ganji,Naidu, Veluru Ramesh,Unelius, C. Rikard
, p. 3234 - 3239 (2017/06/21)
N-Iodosuccinimide (NIS) in pure trifluoroacetic acid (TFA) offers a time-efficient and general method for the iodination of a wide range of mono- and disubstituted benzenes at room temperature, as demonstrated in this paper. The starting materials were generally converted into mono-iodinated products in less than 16 hours at room temperature, without byproducts. A few deactivated substrates needed addition of sulfuric acid to increase the reaction rate. Another exception was methoxybenzenes that preferentially were iodinated by NIS in acetonitrile with only catalytic amounts of TFA.
