42079-76-5

Upstream product

• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 
• 21392-57-4 Dimethyl-chrysin 
• 1775-97-9 flavokawain B 
• 56-23-5 tetrachloromethane 
• 128-08-5 N-Bromosuccinimide 
• 1036-72-2 5,7-dimethoxyflavone 

Downstream Products

• 3570-62-5 5-hydroxy-7,8-dimethoxyflavone 
• 4431-47-4 5,8-dihydroxy-7-methoxyflavone 
• 4443-09-8 norwogonin 
• 23050-38-6 5,7,8-trimethoxy-2-phenyl-chromen-4-one 

Relevant academic research and scientific papers

A highly efficient and environmentally benign synthesis of 6,8-dibromoflavones, 8-bromoflavones, 5,7-dibromoaurones and 7-bromoaurones

Various ring substituted 6,8-dibromoflavones (3a-e) as well as 8-bromoflavones (3f-j) can be synthesized easily from the corresponding 2′-hydroxychalcones (1a-j) in good yields and in two steps under environmentally benign reaction conditions. This can be

[...] flavone, [...] baicalin and to a method for synthesizing Chinese baicalin

The present invention discloses a moslosooflavone synthetic method. The method comprises the steps of (1) 5,7-dimethoxy-8-bromo-flavone is reacted with sodium methylate under the catalysis of a copper salt to generate 5,7,8-trimethoxy flavone; (2) in an i

Ecofriendly synthesis of halogenated flavonoids and evaluation of their antifungal activity

Brominated and chlorinated flavonoids belonging to different classes (flavanones, flavones and catechins) were prepared from the corresponding flavonoids by a simple and ecofriendly procedure based on the use of sodium halides, aqueous hydrogen peroxide and acetic acid. Pure samples of substrates and products were tested against Trichoderma koningii, Fusarium oxysporum and Cladosporium cladosporioides, common saprotrophic soil and seed fungi, potential pathogens for humans and their activity was expressed as linear mycelial growth inhibition (%). Among them, 8-chloro-5,7,3′,4′-tetramethoxyepicatechin 29, a novel catechin derivative, exhibited a remarkable effect against all tested fungi also at low concentrations.

Convergent synthesis of mosloflavone, negletein and baicalein from crysin

An expeditious synthesis of three polyoxygenated flavones: mosloflavone, negletein and baicalein, starting from crysin, an easily available flavone, by a bromination/methoxylation procedure is reported. The convergent synthesis exploits a base induced Wesley-Moser type rearrangement.