420838-27-3Relevant academic research and scientific papers
Isothiourea-Catalyzed Atropselective Acylation of Biaryl Phenols via Sequential Desymmetrization/Kinetic Resolution
Brueckner, Alexander C.,Campbell, Andrew D.,Cheong, Paul Ha-Yeon,Feoktistova, Taisiia,Grove, Markas A.,Munday, Elizabeth S.,Slawin, Alexandra M. Z.,Smith, Andrew D.,Walden, Daniel M.,Young, Claire M.
, p. 7897 - 7905 (2020)
Axially chiral phenols are attractive targets in organic synthesis. This motif is central to many natural products and widely used as precursors to, or directly, as chiral ligands and catalysts. Despite their utility few simple catalytic methods are avail
Facile and highly enantioselective synthesis of axially chiral biaryls by enzymatic desymmetrization
Matsumoto,Konegawa,Nakamura,Suzuki
, p. 122 - 124 (2007/10/03)
The axially chiral biaryls 2 were obtained in high enantioselectivity by desymmetrization of the σ-symmetric biaryl diacetates 1 by lipase-catalyzed hydrolysis.
