4209-25-0

Basic information

• Product Name: Ethanone, 2-chloro-1-(2-chlorophenyl)-
• CAS NO: 4209-25-0
• Molecular Formula: C8H6Cl2O
• Molecular Weight: 189.041
• Mol File: 4209-25-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-1-(2-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-(2-chlorophenyl)-(4209-25-0)
• EPA Substance Registry System: Ethanone, 2-chloro-1-(2-chlorophenyl)-(4209-25-0)

Safety Data

• Hazardous Substances Data: 4209-25-0(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-chloro-1-(2-chlorophenyl)-, also known as 2-Chloroacetophenone, is a chemical compound with the molecular formula C8H6Cl2O. It is a white or off-white crystalline solid that is commonly used as a tear gas and as a chemical intermediate in the production of pesticides and pharmaceuticals. It is classified as a hazardous substance and can cause irritation to the skin, eyes, and respiratory system upon exposure. It is important to handle this compound with caution and follow proper safety protocols when using it in laboratory or industrial settings.

Upstream product

• 54143-03-2 1-chloro-2-(chloroethynyl)benzene 
• 2039-87-4 2-chlorostyrene 
• 67-56-1 methanol 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 10291-39-1 2,2,2-trichloro-1-(2-chloro-phenyl)-ethanol 

Downstream Products

• 130-03-0 thioindoxyl 
• 1311291-96-9 3-(2-chlorophenyl)-2H-benzo[b][1,4]oxazine 
• 1415032-89-1 methyl 6-(2-chlorophenyl)-3-hydroxypicolinate 
• 1415033-06-5 (E)-methyl 6-(2-chlorophenyl)-6-(methoxyimino)-3-oxohexanoate 
• 1415032-75-5 (E)-methyl 6-(2-chlorophenyl)-2-diazo-6-(methoxyimino)-3-oxohexanoate 
• 29261-25-4 (-)-Isoprophenamine 
• 62717-50-4 (R)-(-)-2-(2-chlorophenyl)oxirane 
• 137103-61-8 1-(2-Chloro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol 
• 142657-46-3 1-(4-Bromo-phenyl)-1-(2-chloro-phenyl)-2-imidazol-1-yl-ethanol 

Relevant articles and documents

Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins

A concurrent cascade combining the use of a gold(I) N-heterocyclic carbene (NHC) and an alcohol dehydrogenase (ADH) is disclosed for the synthesis of highly valuable enantiopure halohydrins in an aqueous medium and under mild reaction conditions. The meth

CV-driven Optimization: Cobalt-Catalyzed Electrochemical Expedient Oxychlorination of Alkenes via ORR

Instead of screening reaction conditions by yield-based chemical trial-and-error, potential-based cyclic voltammetry was alternatively employed for optimization of electrochemical oxychlorination of alkenes. With this unconventional screening method, the catalyst system including catalysts, molar ratio of chloride sources and solvents were identified in a rational, time- and energy-efficient manner. The optimal catalytic system in combination with oxygen reduction reaction enabled broad substrate scopes for the desired transformation by taking advantages of persistent radical effect. UV-vis and CV titration experiments confirmed the in-situ formed catalytic species [CoCl5]. Moreover, cyclic voltammetry was applied to obtain mechanistic insights in our reaction system. (Figure presented.).

Iridium-Catalyzed Asymmetric Hydrogenation of Halogenated Ketones for the Efficient Construction of Chiral Halohydrins

Iridium-catalyzed asymmetric hydrogenation of prochiral halogenated ketones was successfully developed to prepare various chiral halohydrins with high reactivities and excellent enantioselectivities under basic reaction condition (up to >99% conversion, 99% yield, >99% ee). Moreover, gram-scale experiment was performed well in the presence of just 0.005 mol% (S/C=20 000) Ir/f-amphox catalyst with 99% yield and >99% ee. (Figure presented.).