4209-95-4

Usage

Structure

Contains a cyclopentanedione ring and a long hydrocarbon chain with a methoxyphenyl group.

Usage

Used as a precursor in the synthesis of various organic compounds.

Applications

Utilized to create pharmaceuticals or agrochemicals.

Fields of Interest

Chemistry, pharmaceuticals, and materials science.

Potential

Has potential applications due to its diverse chemical structure and the variety of reactions it can undergo.

Biological Activity

May have biological activity and could be of interest for further research and development in the medical and pharmaceutical industries.

Upstream product

• 96728-33-5 trans-1-(m-methoxyphenyl)-2-<β-(2-methyl-1,3-dioxocyclopent-2-yl)propionyl>cyclopropane 
• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 70-29-1 diethyl sulphide 
• 57816-04-3 methyl 4-(3-methoxyphenyl)butanoate 
• 1424-71-1 1-diethylamino-6-(m-methoxyphenyl)-2-hexyne 
• 80680-91-7 5-Bromo-2-methoxymethoxy-2-vinyl-pentanenitrile 
• 60235-09-8 1-bromo-6-(m-methoxyphenyl)hexan-3-one 
• 57816-06-5 2-Benzenesulfinyl-6-(3-methoxy-phenyl)-hexan-3-one 
• 57816-02-1 5-(3-methoxyphenyl)-1-methylsulfinyl-pentan-2-one 
• 1424-70-0 1-(4-pentynyl)-3-methoxybenzene 
• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 
• 6943-97-1 (m-methoxyphenyl)propyl bromide 
• 7252-82-6 3-(3-methoxyphenyl)propan-1-ol 
• 80680-92-8 2-Methoxymethoxy-5-(3-methoxy-phenyl)-2-vinyl-pentanenitrile 

Downstream Products

• 18300-15-7 3-methoxy-9,10-secoestra-1,3,5⁽¹⁰⁾,8⁽¹⁴⁾-tetraene-9,17-dione 
• 1159-08-6 1β-Hydroxy-8β-methyl-4-(3-methoxy-phenethyl)-5,6,7,8-tetrahydro-indanon-(5) 
• 966-46-1 rac-3-Methoxy-1,3,5⁽¹⁰⁾,9⁽¹¹⁾-oestratetraen-17-on 

Relevant academic research and scientific papers

Total Synthesis of Aromatic Steroids

The coupling reaction of m-methoxystyrene (1) and 4-bromo-1-diazo-2-butanone (2) over Pd(OAc)2 gave trans and cis (ratio 7:1) cyclopropane derivatives 3a and 3b, which were used for the alkylation of 2-methylcyclopentane-1,3-dione to afford triketones 4a

A HIGHLY CONVERGENT AND FLEXIBLE STRATEGY FOR THE SYNTHESIS OF A-RING AROMATIC STEROIDS

Using Hendrickson's criteria for systematic synthesis design, a strategy featuring a linear six carbon synthon (7) for bis-annulation has been devised for economic, flexible and highly convergent syntheses of A-ring aromatic steroids.

Synthesis of gon-4-enes

1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17α-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.

Synthesis of 13-alkyl-gon-4-ones

The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.