7252-82-6

Basic information

• Product Name: 3-(3-METHOXY-PHENYL)-PROPAN-1-OL
• Synonyms: 3-(3-METHOXY-PHENYL)-PROPAN-1-OL;m-Methoxyphenyl-1-propanol;3-(m-Methoxyphenyl)-1-propanol;1-Propanol, 3-(m-methoxyphenyl)-;3-(m-Methoxyphenyl)propanol;Benzenepropanol, 3-methoxy- (9ci);Brn 1863731;Nsc 54447
• CAS NO: 7252-82-6
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• Mol File: 7252-82-6.mol
• Article Data: 41

Chemical Properties

• Boiling Point: 155-157 °C(Press: 15 Torr)
• Appearance: /
• Density: 1.037±0.06 g/cm3(Predicted)
• PKA: 15.08±0.10(Predicted)
• CAS DataBase Reference: 3-(3-METHOXY-PHENYL)-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-METHOXY-PHENYL)-PROPAN-1-OL(7252-82-6)
• EPA Substance Registry System: 3-(3-METHOXY-PHENYL)-PROPAN-1-OL(7252-82-6)

Safety Data

• Hazardous Substances Data: 7252-82-6(Hazardous Substances Data)

Usage

General Description

3-(3-Methoxy-phenyl)-propan-1-ol is an organic compound that belongs to the class of alcohols. Its chemical structure consists of a propyl chain with a hydroxyl group (OH) at one end and a 3-methoxy-phenyl group attached to the second carbon atom of the chain. 3-(3-METHOXY-PHENYL)-PROPAN-1-OL is commonly used in the synthesis of various pharmaceuticals, fragrances, and other organic compounds. It is also used as a flavoring agent in the food industry. The presence of the 3-methoxy-phenyl group gives the compound its characteristic aroma and makes it valuable in the production of fragrances and perfumes.

Upstream product

• 141-82-2 malonic acid 
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• 27913-19-5 3-(3-methoxyphenyl)prop-2-yn-1-ol 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 33877-04-2 ethyl (E)-3-(3-methoxyphenyl)acrylate 
• 24743-14-4 1-allyl-3-methoxybenzene 
• 50704-52-4 methyl 3-(3-methoxyphenyl)propionate 
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• 75-21-8 oxirane 
• 874-98-6 1-bromomethyl-3-methoxybenzene 
• 7116-39-4 3-(3-methoxyphenyl)propanoic acid ethyl ester 

Downstream Products

• 185254-89-1 3-(3-methoxyphenyl)prop-1-yl acetoacetate 
• 723287-09-0 3-(3-methoxyphenyl)propyl sulfamate 
• 18300-15-7 3-methoxy-9,10-secoestra-1,3,5⁽¹⁰⁾,8⁽¹⁴⁾-tetraene-9,17-dione 
• 1424-70-0 1-(4-pentynyl)-3-methoxybenzene 
• 4209-95-4 6-(m-methoxyphenyl)-1-(2-methyl-1,3-dioxocyclopent-2-yl)hexan-3-one 
• 1424-71-1 1-diethylamino-6-(m-methoxyphenyl)-2-hexyne 
• 1229-32-9 (+/-)-3-methoxyestra-1,3,5⁽¹⁰⁾,6,8-pentaen-17-one 
• 966-46-1 rac-3-Methoxy-1,3,5⁽¹⁰⁾,9⁽¹¹⁾-oestratetraen-17-on 
• 1159-08-6 1β-Hydroxy-8β-methyl-4-(3-methoxy-phenethyl)-5,6,7,8-tetrahydro-indanon-(5) 
• 6943-97-1 (m-methoxyphenyl)propyl bromide 
• 310466-18-3 Methanesulfonic Acid 3-(3-Methoxy-phenyl)-propyl Ester 
• 107318-70-7 3-(3-methoxyphenyl)propyl 4-methylbenzenesulfonate 
• 1417802-03-9 3-(2-(2,6-dimethoxy-5-((2-oxo-2H-pyran-4-yl)oxy)-9,10-dihydrophenanthren-3-yl)-5-methoxyphenyl)propanal 
• 1417802-01-7 6-(2-(3-hydroxypropyl)-4-methoxyphenyl)-3,7-dimethoxy-9,10-dihydrophenanthren-4-ol 

Relevant articles and documents

Synthesis of carbon-14-labeled isotopomer of 6-(4-methanesulfonylphenyl)-5- [4-(2-piperidin-1-yl-ethoxy)phenoxy]-naphthalen-2-ol HCL salt (LY2066948-[ 14C] HCL salt)

Carbon-14-labeled 6-(4-methanesulfonylphenyl)-5-[4-(2-piperidin-1-yl- ethoxy)phenoxy]naphthalen-2-ol, a novel selective estrogen receptor modulator (SERM) was synthesized. The key component, 6-methoxy-1-tetralone-[carbonyl- 14C], was synthesize

Synthetic and Mechanistic Studies on 2,3-Dihydrobenzo[ b ][1,4]-oxaselenines Formation from Selenocyanates

An expedient preparation of selenium-containing hetero-cycles via an m -chloroperbenzoic acid-mediated seleno-annulation starting from selenocyanate derivatives is described. In spite of its significance, this cyclization reaction is virtually understudied not only from the point of view of its scope, but also from the mechanistic aspects associated to this remarkable transformation. In this sense, several selenocyanate and thiocyanate derivatives bearing an aromatic ring were evaluated as substrates under different reaction conditions of this interesting cyclization yielding important insights on its scope as well as relevant information on the reaction mechanism.

DIRECT C-H AMINATION AND AZA-ANNULATION

In some aspects, the present disclosure provides methods of aminating an aromatic compound comprising reacting an aminating agent with an aromatic compound in the presence of a rhodium catalyst. In some embodiments, the methods may comprise aminating an aromatic compound which contains multiple different functional groups. The methods described herein may also be used to create bicyclic system comprising reacting an intramolecular aminating agent with an aromatic ring to obtain a second ring containing a nitrogen atom. In another aspect, the methods described herein may also be used to create a cyclic aliphatic cyclic/poly cyclic amine system comprising a reacting an intramolecular aminating agent by insertion into a C(sp3)-H bond.