421-52-3

Usage

Uses

Used in Organic Synthesis:
2,2,2-Trifluoroethanethioamide serves as a source of nucleophilic 2,2,2-trifluoroethylthio anion, which is capable of participating in a variety of chemical reactions. Its reactivity and the presence of fluorine atoms make it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2,2,2-trifluoroethanethioamide is utilized as a building block for the synthesis of various drugs. Its unique chemical properties allow for the creation of novel therapeutic agents with potential applications in treating a range of medical conditions.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, 2,2,2-trifluoroethanethioamide is employed as a key component in the development of new pesticides and other agricultural chemicals. Its incorporation into these products can enhance their effectiveness and selectivity, contributing to more efficient and sustainable agricultural practices.
Overall, the diverse applications of 2,2,2-trifluoroethanethioamide across different industries highlight its importance as a chemical intermediate and building block, underpinning its value in modern chemical research and development.

InChI:InChI=1/C2H2F3NS/c3-2(4,5)1(6)7/h(H2,6,7)

Upstream product

• 353-85-5 trifluoroacetonitrile 
• 354-38-1 2,2,2-trifluoroacetamide 
• 19172-47-5 Lawessons reagent 
• 785825-81-2 trifluoromethylhydrazine 
• 7783-06-4 hydrogen sulfide 

Downstream Products

• 7387-69-1 N-benzyl-2,2,2-trifluoroacetamide 
• 70529-37-2 4,5-diphenyl-2-trifluoromethyl-thiazole 
• 70529-36-1 4,5-bis-(4-chloro-phenyl)-2-trifluoromethyl-thiazole 
• 70529-35-0 4,5 bis(4 methoxyphenyl) 2 (trifluoromethyl)thiazole 
• 177561-43-2 5-(4-fluorophenyl)-4-(4-methylthiophenyl)-2-trifluoromethylthiazole 
• 177561-23-8 4-(4-fluorophenyl)-5-(4-methylthiophenyl)-2-trifluoromethylthiazole 
• 133046-46-5 Ethyl 2-(trifluoromethyl)thiazole-4-carboxylate 
• 20570-36-9 Trifluordithio-essigsaeure 
• 1384866-42-5 N-[1-(benzoyldithio)-2,2,2-trifluoroethyl]benzamide 
• 131748-96-4 ethyl 2-(trifluoromethyl)thiazole-5-carboxylate 
• 1263286-63-0 ethyl 4-methyl-2-(trifluoromethyl)-1,3-thiazole-5-carboxylate 
• 1402003-85-3 2-[2-(trifluoromethyl)-1,3-thiazol-4-yl]phenol 
• 936129-78-1 ethyl 5-phenyl-2-(trifluoromethyl)-1,3-thiazole-4-carboxylate 

Relevant academic research and scientific papers

Cycloaddition reactions of polyfluoroalkylthioncarboxylic acid derivatives with dimethyl acetylenedicarboxylate (DMAD)

Polyfluoroalkyldithiocarboxylates react with dimethyl acetylenedicarboxylate (DMAD) to give 2-polyfluoroalkyl-1,3-dithioles and/or 2-polyfluoroalkylidene-1,3-dithioles depending on the substituent at the thiolic sulfur atom and on the length of the polyfluoroalkyl chain. Amides of polyfluoroalkylthioncarboxylic acids with DMAD give 2-methoxy-2-polyfluoroalkyl-5-methoxycarbonylmethylene- thiazolidin-4-ones.

Compound synthesized from new thiazole monomer including electron withdrawing group and manufacturing method thereof

The present invention relates to a compound synthesized with a novel thiazole monomer including an electron withdrawing group and a producing method thereof. The compound by the present invention is synthesized by using a thiazole monomer of a new structu

HETEROARYL SUBSTITUTED BETA-HYDROXYETHYLAMINES FOR USE IN TREATING HYPERGLYCAEMIA

There is herein provided a compound of formula (I) or a pharmaceutically acceptable salt thereof,wherein the ring containing Q1to Q5, and the groups R1, R2 and R3, have meanings as provided in the description.

SUBSTITUTED OXAZOLE- AND THIAZOLE-BASED CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS II

The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

2,3-SUBSTITUTED FUSED BICYCLIC PYRIMIDIN-4(3H)-ONES WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)

Compounds of formula (I) which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VRl, also known as TRPVl).

PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

5-carboxanilido-2,4-bis-trifluoromethylthiazoles and their use to control rice blast

The present invention provides 5-carboxanilido-2,4-bis-trifluoromethylthiazoles and their compositions. The compounds and compositions are effective for controlling fungal diseases on plants. They are particularly effective for controlling rice blast.

5-Carboxanilido-haloalkylthiazoles as antimicrobial and marine antifouling agents

The present invention relates to a method for inhibiting the growth of microorganisms and marine organisms at a locus. In particular, the present invention relates to the use of certain 5-carboxanilido-haloalkylthiazoles as antimicrobial and marine antifouling agents.

Microbicidal salts of 5-carboxanilido-haloalkylthiazoles

Compounds of the formula:whereinA is a strong base cation;R1and R2are independently (C1-C5)alkyl or (C1-C2)haloalkyl, provided that at least one of R1and R2is (C1-C2)haloalkyl;each R is independently halo, halo(C1-C5)alkyl, halo(C1-C5)alkoxy, nitro, cyano, pentahalosulfur, halomethylthio, haloethylthio, (C1-C2)alkylsulfinyl, halo(C1-C2)alkylsulfinyl, (C1-C2)alkylsulfonyl, or halo(C1-C2)alkylsulfonyl; andn is from one to five,are useful as fungicides, microbicides, marine antifoulants, and termiticides, compositions containing those compounds, and methods for their use.