42122-34-9

Basic information

• Product Name: 2-Propynoyl chloride, 3-(4-chlorophenyl)-
• CAS NO: 42122-34-9
• Molecular Formula: C9H4Cl2O
• Molecular Weight: 199.036
• Mol File: 42122-34-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Propynoyl chloride, 3-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoyl chloride, 3-(4-chlorophenyl)-(42122-34-9)
• EPA Substance Registry System: 2-Propynoyl chloride, 3-(4-chlorophenyl)-(42122-34-9)

Safety Data

• Hazardous Substances Data: 42122-34-9(Hazardous Substances Data)

Upstream product

• 3240-10-6 (4-chlorophenyl)propiolic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 1615-02-7 p-chlorocinnamic acid 
• 31357-32-1 α,β-dibromo-p-chlorohydrocinnamic acid 
• 20026-96-4 ethyl 3-(4-chlorophenyl)propiolate 

Downstream Products

• 76071-81-3 p-chlorophenylpropiolic acid ethyleneimide 
• 42122-09-8 3-(4-chlorophenyl)-2-propynamide 
• 1195777-24-2 N-cyclopropylmethyl-14β-[4'-chlorophenylpropioloylamino]-7,8-dihydronorcodeinone 
• 131292-29-0 6-(4-chlorophenyl)-2-methylhexa-3,5-diyn-2-ol 
• 131292-05-2 ethyl 5-(4-chlorophenyl)-3-oxo-2-triphenylphosphoranylidenepent-4-ynoate 
• 107524-48-1 1-(4-chloro-phenyl)-naphthalene-2,3-dicarboxylic acid-anhydride 
• 101579-16-2 7-chloro-1-phenyl-naphthalene-2,3-dicarboxylic acid-anhydride 
• 7495-50-3 1-(4-chlorophenyl)-7-chloro-2,3-naphthalenedicarboxylic anhydride 
• 132180-92-8 7-chloro-1-(2-chloro-phenyl)-naphthalene-2,3-dicarboxylic acid-anhydride 

Relevant articles and documents

AlBr3-Promoted stereoselective anti-hydroarylation of the acetylene bond in 3-arylpropynenitriles by electron-rich arenes: Synthesis of 3,3-diarylpropenenitriles

Reactions of 3-arylpropynenitriles (ArC≡CCN) with electron-rich arenes (Ar'H, benzene and its polymethylated derivatives) under the action of aluminum bromide (AlBr3, 6 equiv) at room temperature for 0.5-2 h result in the stereoselective formation of 3,3-

Carbene-catalyzed LUMO activation of alkyne esters for access to functional pyridines

A carbene-catalyzed LUMO activation of α,β-unsaturated alkyne esters is reported. This catalytic process allows for effective reactions of alkyne esters with enamides to synthesize functional pyridines via simple protocols. A previously unexplored unsaturated alkyne acyl azolium intermediate is involved in the key step of the reaction.

Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

Convenient and efficient synthesis of a new environmentally sensitive chlorine-substituted 2,3-naphthalimide-based fluorophore is reported. Benzotriazole carboxyl group activation of the 6-chloro-fluorophore enabled quick labeling of free and Fmoc-protected amino acids. The photophysical properties of the compounds obtained include high quantum yields in solvents of different polarity: water, methanol, acetonitrile and hexane.