42152-36-3

Upstream product

• 100-52-7 benzaldehyde 
• 137-07-5 2-amino-benzenethiol 
• 15111-14-5 2-iodo-N-(phenylmethylene)-benzenamine 

Downstream Products

• 883-93-2 2-Phenylbenzothiazole 
• 25069-68-5 2,3-diphenyl-3,4-dihydro-2H-benzo[b][1,4]thiazine 
• 31230-83-8 2-Phenylbenzothiazolin 

Relevant academic research and scientific papers

Synthesis and characterization of cadmium sulfide nanocrystals in the presence of a new sulfur source via a simple solvothermal method

CdS nanocrystals were successfully prepared using solvothermal strategies that employed Cd(NO3)2·4H2O and a new sulfurising agent from the class of thio Schiff-bases as starting materials, and propylene glycol (PG) as the solvent. X-ray diffraction (XRD) patterns and transmission electron microscopy (TEM) images show that the synthesized CdS nanostructures have hexagonal and cubic structures with a diameter of about 12 nm. The formation of CdS nanoparticles and their structure, morphology and elemental composition were studied by means of FT-IR, XRD, SEM, HR-TEM and EDAX. The optical properties of the products were characterized by optical absorption spectroscopy. Based on the results of the experiments, it was found that the reaction temperature, duration and the solvent play significant roles in the formation of the CdS nanoparticles. The initiative of this work is the application of a new thio Schiff-base (2-(benzylidene amino) benzenethiol (C13H11NS)) as a complexing and sulfurising agent for the synthesis of CdS nanostructures. A possible formation mechanism of the nanoparticles is discussed.

Structural and spectroscopic characterization of prepared Ag2S nanoparticles with a novel sulfuring agent

Ag2S nanoparticles were prepared by a solvothermal process via reaction of Ag(NO3) and a new sulfuring agent from class of thio Schiff-base (2-(benzylidene amino) benzenethiol (C13H 11NS)) in presence of various solvents. Spectra such as X-ray diffraction (XRD), transmission electron microscopy (TEM), selected area electron diffraction (SEAD), ultraviolet-visible (UV-Vis) spectroscopy, thermo gravimetric-differential thermal analysis (TG-DTA), and Fourier transform Infrared (FT-IR) employed to characterize the synthesized products. Results of this paper indicate that shape and size of the silver sulfide can be controlled by means of setting certain reaction parameters such as the reaction temperature, presence of surfactant, and type of solvent. Silver sulfide nanoparticles with different morphology and size successfully prepared. In addition, the growth mechanisms of the Ag2S nanoparticles discussed preliminarily.

OMS-2/H2O2/Dimethyl Carbonate: An Environmentally-Friendly Heterogeneous Catalytic System for the Oxidative Synthesis of Benzoxazoles at Room Temperature

A manganese octahedral molecular sieve (OMS-2) was found to be an efficient and recyclable heterogeneous catalyst for the oxidative synthesis of benzoxazoles in the gram-scale from phenolic imines at room temperature. H2O2 and biobased reagent dimethyl carbonate (DMC) were successfully employed as the environmentally friendly oxidant and solvent, respectively, in an OMS-2-catalysted redox reaction for the first time. Benzoxazoles could also be obtained from N-substituted 2-aminophenols via Cu(OH)x/OMS-2-catalyzed sequential oxidative transformation at elevated temperatures.

Synergism in semiconducting nanocomposites: Visible light photocatalysis towards the formation of C-S and C-N bonds

A simple, facile and visible light driven photochemical synthesis of 2-substituted benzothiazoles and 2-substituted benzimidazoles is achieved with CdSe nanocomposites as a photocatalyst. These nanocomposites are prepared by the molecular self assembly of 2-3 nm sized zinc blende CdSe phase within the layers of montmorillonite (MMT) through intercalation forming lamellar structure. CdSe/MMT exhibits excellent photocatalytic activity towards the synthesis of benzazoles using aliphatic, aromatic and heterocyclic aldehydes with better yields, and the efficiency is retained up to five cycles. XRD, XPS and Raman analyses of fresh and used CdSe/MMT reveal the passivation of structural defects due to the formation of a thin layer of CdO on the photocatalyst surface. The mixed phase of CdSe-CdO facilitates the generation of a hetero-junction on the CdSe/MMT surface, which is beneficial for photostability and sustainability. This process is also efficient under solar light and provides easy product isolation on the gram scale. Thus, it may be regarded as a greener methodology for the synthesis of bioactive scaffolds with excellent yields and high chemoselectivity using a tailor-made photocatalyst.

An efficient and environmental benign synthesis of 2-benzimidazoles and 2-benzothiazoles using CeCl3-NaI as catalyst

A one-pot condensation of an aldehyde with 1,2-phenylenediamine or 2-aminothiophenol in dimethyl carbonate at 100°C under O2 in the presence of catalytic amounts of CeCl3-NaI gave an imine intermediate, which cyclised and dehydrogenated to give 2-arylbenzimidazoles or 2-arylbenzothiazoles in good yields.

The efficient o-benzenedisulfonimide catalysed synthesis of benzothiazoles, benzoxazoles and benzimidazoles

O-Benzenedisulfonimide has been used to efficiently catalyse the reaction between 2-aminothiophenol, 2-aminophenol, o-phenylenediamine and various ortho esters (28 examples; average yield 90%) or aldehydes (17 examples; average yield 72%) giving the corresponding benzofused azoles in excellent yields. Reaction conditions were very simple. In addition, other carboxylic acid derivatives have been tested and gave good results. The catalyst was easily recovered and reused. ARKAT-USA, Inc.

Synthesis of benzothiazoles through copper-catalyzed one-pot three-component reactions with use of sodium hydrosulfide as a sulfur surrogate

Copper-catalyzed one-pot three-component reactions of 2-iodoanilines, aldehydes, and NaSH·n H2O afford benzothiazoles in good yields. When CuCl was employed as a catalyst in the absence of a ligand, a variety of aromatic aldehydes and substituted 2-iodoanilines reacted with NaSH·n H2O to produce the corresponding 2-arylbenzothiazoles in 70-98 % yields. The copper catalyst plays a key role in C-S bond formation between NaSH·n H2O and the aryl iodide that was formed from the condensation of 2-iodoaniline and aldehyde. It was found that NaSH·n H2O functions as a sulfur surrogate and oxidant in the formation of benzothiazole. 2-Iodoanilines, aldehydes, and NaSH·n H2O afford benzothiazoles in a one-pot reaction in the presence of a copper catalyst. The desired products can be obtainedin moderate to good yields. The copper catalyst plays a key role in C-S bond formation between aryl iodides and NaSH·n H2O. Copyright

Facile preparation of 2-substituted benzoxazoles and benzothiazoles via aerobic oxidation of phenolic and thiophenolic imines catalyzed by polymer-incarcerated platinum nanoclusters

Platinum nanoclusters supported on a polymer/carbon black composite material was found to be an excellent catalyst for the oxidative cyclization of phenolic and thiophenolic Schiff bases to 2-substituted benzoxazoles and benzothiazoles under ambient conditions. Copyright

Simple and efficient one-pot synthesis of 2-substituted benzoxazole and benzothiazole

2-Substituted benzoxazole and benzothiazole were synthesized from condensation of aldehyde and 2-aminophenol or 2-aminothiophenol via a one-pot process using diethyl bromo phoshonate and tert-butyl hypochlorite.

Electrooxidative cyclization of benzylideneaminothiophenols to the corresponding 2-arylbenzothiazoles

Several benzylideneaminothiophenols were electrochemically oxidized in methanol containing sodium acetate as the supporting electrolyte, to afford the corresponding 2-arylbenzothiazols. The reaction proceeded via intramolecular cyclization involving the formation of a new bond between the benzylic carbon of the substrate and the sulfur of the thiol group. Based on the yields, room temperature and the use of two equivalents of sodium acetate relative to the substrate as the supporting electrolyte were found to be the optimal reaction conditions. The electrooxidation presumably involves a two-electron oxidation process.