42160-26-9 Usage
General Description
2-amino-4-methyl-5-phenylthiophene-3-carbonitrile is a chemical compound that belongs to the thiophene family. It consists of a thiophene ring with an amino group at the 2-position, a methyl group at the 4-position, a phenyl group at the 5-position, and a cyano group at the 3-position. 2-amino-4-methyl-5-phenylthiophene-3-carbonitrile is used in the field of organic chemistry as a building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable intermediate in the production of complex organic molecules. Additionally, it is also utilized in the development of materials and as a research tool in chemical sciences. Overall, 2-amino-4-methyl-5-phenylthiophene-3-carbonitrile is a versatile compound with multiple applications in various scientific and industrial fields.
Check Digit Verification of cas no
The CAS Registry Mumber 42160-26-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,1,6 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 42160-26:
(7*4)+(6*2)+(5*1)+(4*6)+(3*0)+(2*2)+(1*6)=79
79 % 10 = 9
So 42160-26-9 is a valid CAS Registry Number.
42160-26-9Relevant academic research and scientific papers
Substituted 2-Aminothiopen-derivatives: A potential new class of GluR6-Antagonists
Briel,Rybak,Kronbach,Unverferth
experimental part, p. 69 - 77 (2010/03/24)
In the course of search for new therapeutic agents against epilepsy new inhibitors for the kainate receptor subtypes GluR5 and GluR6 were synthesized. We were able to synthesize new substituted thieno[2,3-d]pyrimidines 3a,b, 4a,b, 5a,b as well as thiophene-3-carboxamides 2a-d and a multitude of substituted 4-methyl-5-phenylthiophene-3-carboxylic acids. All compounds described herein were tested for their antagonistic effect towards the kainate receptor subtypes GluR5 and GluR6. The highest activity was observed for ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate 1c with an IC50 = 0.75 μM at the GluR6 receptor.
Process for the manufacture of heterocyclic compounds
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, (2008/06/13)
Process for manufacture of the heterocyclic compounds of the formula: STR1 wherein X is cyano, acyl, alkylsulphonyl, arylsulphonyl, optionally substituted alkoxycarbonyl, nitro, phenyl or sulphamoyl, and Y is hydrogen, optionally substituted alkyl or opti
