42182-48-9Relevant academic research and scientific papers
Alkylation reactions of benzothiazoles with N,N-dimethylamides catalyzed by the two-component system under visible light
Weng, Jian-Quan,Xu, Wen-Xiu,Dai, Xiao-Qiang,Zhang, Jun-Hui,Liu, Xing-Hai
, p. 390 - 396 (2019)
Eosin Y/K2S2O8 catalyzed C2-alkylation reactions of benzothiazoles with N,N-dimethylamides under visible light have been developed. The reactions completed smoothly in the presence of Eosin Y as the photocatalyst and Ksub
Amidoalkylation of Sulfonylheteroarenes with Alkylamides through a Radical Chain Mechanism
Ikeda, Yuko,Matsukawa, Yuko,Shirakawa, Eiji,Yonekura, Kyohei
supporting information, p. 794 - 797 (2021/01/18)
In the presence of a substoichiometric amount of a tert-butoxy radical precursor and a base, alkylamides were found to be heteroarylated at their α-C?H bonds with sulfonylheteroarenes through homolytic aromatic substitution, where a radical chain is operative.
Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate
He, Tao,Li, Hongji,Li, Pinhua,Wang, Lei
supporting information; experimental part, p. 8946 - 8948 (2011/10/02)
A novel and simple method for the direct amidation of azoles with formamides has been developed. The reaction could occur smoothly in the presence of tert-butyl perbenzoate (TBPB) as an oxidant under metal- and base-free conditions. Direct dehydrogenative
Azole-N-acetonitriles as carbonyl synthons: A one-pot preparation of heteroaryl amides from halides
Zhang, Zhongxing,Yin, Zhiwei,Kadow, John F.,Meanwell, Nicholas A.,Wang, Tao
, p. 2323 - 2326 (2007/10/03)
Azole-N-acetonitrile derivatives were utilized as synthons for an ambident carbonyl moiety via a strategy relying upon sequential base-mediated S NAr substitution of a 2-halo heterocycle, in situ oxidation, and amine displacement. This strategy allows prompt and efficient synthesis of N-containing heteroaryl amides directly from the corresponding halides via a one-pot process.
