4221-80-1

Usage

Uses

Used in Polymer Industry:
2,4-Di-tert-butylphenyl 3,5-di-tert-butyl-4-hydroxybenzoate is used as a stabilizer for [application reason] to prevent the degradation of pigmented polymers, especially in cases where the pigment itself can promote polymer degradation. Its non-absorption of visible light ensures that it does not alter the initial color of the substrate or polymer, preserving the material's original appearance.
Used in Pigmented Polymers:
In the context of pigmented polymers, 2,4-Di-tert-butylphenyl 3,5-di-tert-butyl-4-hydroxybenzoate is used as a protective agent for [application reason] to safeguard the polymer from degradation caused by the pigment. Its ability to not affect the visible light spectrum makes it a preferred choice for maintaining the color integrity of the pigmented polymers.

Flammability and Explosibility

Notclassified

InChI:InChI=1/C29H42O3/c1-26(2,3)19-13-14-23(20(17-19)27(4,5)6)32-25(31)18-15-21(28(7,8)9)24(30)22(16-18)29(10,11)12/h13-17,30H,1-12H3

Synthetic route

2,4-di-tert-Butylphenol (96-76-4) + methyl 3,5-di-tert-butyl-4-hydroxybenzoate (2511-22-0) → 3,5-di-tert-butyl-4-hydroxybenzoic acid 2,4-di-tert-butyl-phenyl ester (4221-80-1)

Conditions	Yield
Stage #1: 2,4-di-tert-Butylphenol With sodium methylate at 120℃; under 675.068 Torr; for 10h; Stage #2: methyl 3,5-di-tert-butyl-4-hydroxybenzoate at 150℃; for 5h; Reagent/catalyst; Temperature; Pressure;	90%

2,4-di-tert-Butylphenol (96-76-4) + 3,5-Di-tert-butyl-4-hydroxybenzoic acid (1421-49-4) → 3,5-di-tert-butyl-4-hydroxybenzoic acid 2,4-di-tert-butyl-phenyl ester (4221-80-1)

Conditions	Yield
With oxalyl dichloride In toluene at 80 - 120℃; for 2h; Temperature; Solvent; Reagent/catalyst;	88.1%
With trichlorophosphate In 5,5-dimethyl-1,3-cyclohexadiene at 20 - 80℃; for 30h;	76%

2,4-di-tert-Butylphenol (96-76-4) + tert-butyl 3,5-di-tert-butyl-4-hydroxybenzoate (51517-24-9) → 3,5-di-tert-butyl-4-hydroxybenzoic acid 2,4-di-tert-butyl-phenyl ester (4221-80-1)

Conditions	Yield
Stage #1: 2,4-di-tert-Butylphenol With lithium methanolate at 140℃; under 712.571 Torr; for 6h; Stage #2: tert-butyl 3,5-di-tert-butyl-4-hydroxybenzoate at 150℃; for 5h;	72%

Upstream product

• 96-76-4 2,4-di-tert-Butylphenol 
• 1421-49-4 3,5-Di-tert-butyl-4-hydroxybenzoic acid 
• 2511-22-0 methyl 3,5-di-tert-butyl-4-hydroxybenzoate 
• 51517-24-9 tert-butyl 3,5-di-tert-butyl-4-hydroxybenzoate 

Relevant academic research and scientific papers

Method for preparing phenyl benzoate ultraviolet absorber through ester exchange

The invention provides a method for preparing a phenyl benzoate ultraviolet absorber through ester exchange. The method comprises the steps that at least one hindered phenol in the formula I reacts with alkali at 100-140 DEG C to obtain hindered phenol salt, then the hindered phenol salt reacts with at least one benzoate compound of the formula II at 110-195 DEG C, and the absorber is obtained. Accordingly, the disadvantages of being high in production cost, large in industrial waste water and the like caused by the traditional acyl chloride process are avoided; the disadvantages of poor product selectivity caused by an esterification method, low atomic utilization rate caused by an acid anhydride method and the like are avoided; in addition, the method has the advantages of being low in production cost, easy to operate and implement, high in reaction speed, high in single yield of products and capable of recycling and mechanically applying unreacted raw materials, so that the method is more suitable for industrial production.

Preparation method for 2,4-di-tert-butylphenyl 3,5-di-tert-butyl-4-hydroxybenzoate

The invention discloses a preparation method for 2,4-di-tert-butylphenyl 3,5-di-tert-butyl-4-hydroxybenzoate, belongs to the field of synthetic organic chemistry, and aims at solving the problems thatthere are too many reaction steps, a large number of solvent varieties and solvents, and too many byproducts and the post-treatment is complicated in existing methods. The preparation method comprises the steps that A, reaction section; benzoic acid,3,5-bis(1,1-dimethylethyl)-4-hydroxy and 2,4-di-tert-butylphenol are taken as raw materials, the raw materials are dissolved in organic solvent, an acylation reagent is added dropwisely and reaction is performed; B, post-treatment section; cooling is conducted after the reaction is completed, alkaline liquor is added into reaction liquid to conduct stirring to remove excess acylation reagent and unreacted carboxylic acid, organic phase is washed by warm water until the pH of an aqueous layer is neutral, the reaction liquid is allowed to standfor stratification, the organic phase is dried by using anhydrous sodium sulfate, the solvent is removed by evaporation through reducing pressure to obtain crude products, and purification is conducted by using alcohol to obtain end products. The method has the advantages of being short in reaction time, simple in operation, high in percent conversion and suitable for industrial production.

Phenylalkanoic acid esters and their use as antioxidants

Compounds of formula (I): STR1 wherein: R1 represents an alkyl group having from 1 to 6 carbon atoms; R2 represents an alkyl group having from 8 to 24 carbon atoms; EO represents an ethyleneoxy group; PO represents a propyleneoxy group; k is 0 or an integer from 1 to 10; and m is an integer from 1 to 4; provided that the total of (k+m) is greater than 1 and not greater than 10; are useful as antioxidant stabilizers for polymeric materials.