2511-22-0

Basic information

• Product Name: METHYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE
• Synonyms: METHYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE;3,5-DI-TERT-BUTYL-4-HYDROXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0198;methyl 3,5-bis-tert-butyl-4-hydroxybenzoate
• CAS NO: 2511-22-0
• Molecular Formula: C₁₆H₂₄O₃
• Molecular Weight: 264.36
• EINECS: 219-729-2
• Product Categories: Aromatic Esters
• Mol File: 2511-22-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 164-166°C
• Boiling Point: 334.8°Cat760mmHg
• Flash Point: 126.4°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 6.41E-05mmHg at 25°C
• Refractive Index: 1.503
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• PKA: 9.19±0.40(Predicted)
• BRN: 2218125
• CAS DataBase Reference: METHYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE(2511-22-0)
• EPA Substance Registry System: METHYL 3,5-DI-TERT-BUTYL-4-HYDROXYBENZOATE(2511-22-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 2511-22-0(Hazardous Substances Data)

Usage

Uses

Methyl 3,5-Di-tert-butyl-4-hydroxybenzoate is an antioxidant; used in method for preparaing high-efficiency composite antioxidant and application.

InChI:InChI=1/C16H24O3/c1-15(2,3)11-8-10(14(18)19-7)9-12(13(11)17)16(4,5)6/h8-9,17H,1-7H3

Upstream product

• 2511-25-3 2,6-Di-tert.-butyl-4-methoxycarbonyl-phenoxyl 
• 67-56-1 methanol 
• 1421-49-4 3,5-Di-tert-butyl-4-hydroxybenzoic acid 
• 75-78-5 dimethylsilicon dichloride 
• 186581-53-3 diazomethane 
• 23093-16-5 3,5-di-tert-butyl-4-hydroxybenzaldehyde dimethyl acetal 
• 1620-98-0 3,5-di-t-butyl-4-hydroxybenzaldehyde 
• 40056-43-7 3,5-di-tert-butyl-4-hydroxybenzoyl chloride 
• 1988-88-1 2,6-di-tert-butyl-4-cyanophenol 
• 732-26-3 2,4,6-tri-tert-butylphenoxol 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 27329-74-4 (4-Bromo-2,6-di-tert-butylphenoxy)trimethylsilane 
• 67739-24-6 (3,5-Di-t-butyl-4-hydroxyphenyl)-glyoxylsaeurenitril 
• 87-97-8 2,6-di-tert-butyl-4-methoxymethylene-phenol 

Downstream Products

• 148991-72-4 bis(1-methylimidazolyl)(3,5-di-tert-butyl-4-hydroxyphenyl)hydroxymethane 
• 719-22-2 2,6-Di-tert-butyl-1,4-benzoquinone 
• 40095-35-0 3-tert-Butyl-4-hydroxy-5-nitro-benzoic acid methyl ester 
• 81389-62-0 3,5-Di-tert-butyl-3-hydroperoxy-4-oxo-cyclohexa-1,5-dienecarboxylic acid methyl ester 
• 220548-38-9 4-[bis-(3-tert-butyl-4,5-dihydroxy-phenyl)-methylene]-2,6-di-tert-butyl-cyclohexa-2,5-dienone 
• 219948-13-7 bis(5'-tert-butyl-3',4'-bis(methoxymethyloxy)phenyl)-3,5-di-tert-butyl-4-oxophenylmethane 
• 51517-24-9 tert-butyl 3,5-di-tert-butyl-4-hydroxybenzoate 
• 1620-64-0 ethyl 4-hydroxy-3,5-di-tert-butylbenzoate 
• 71579-48-1 4-Hydroxy-3.5-di-tert-butyl-benzoesaeure-propylester 
• 94253-63-1 4-Hydroxy-3.5-di-tert-butyl-benzoesaeure-isopropylester 
• 40095-34-9 3-tert-Butyl-4-hydroxy-5-nitro-benzoesaeure 
• 97879-54-4 3,5-Di-tert.-butyl-p-benzochinonoxim-(2-oxo-1,3-di-tert.-butyl-5-carbaethoxy-cyclohexadien-(3,5)-yl)-aether 
• 97829-15-7 3,5-Di-tert.-butyl-p-chinonoxim-(2-oxo-1,3-di-tert.-butyl-5-carboisopropoxy-cyclohexadien-(3,5)-yl)-aether 
• 97829-13-5 C₃₂H₄₆O₈ 

Relevant articles and documents

Oxidative Rearrangement of 3,5-Di-tert-butyl-4-hydroxybenzaldehyde Acetals

3,5-Di-tert-butyl-4-hydroxybenzaldehyde acetals rearrange to various esters when oxidized with potassium ferricyanide in alkaline medium.

A 3, 5 - di-tert-butyl - 4 - hydroxy-benzoic acid methyl ester (by machine translation)

The present invention provides anti-oxidant 3, 5 - di-tert-butyl - 4 - hydroxy-benzoic acid methyl ester, which belongs to the field of organic chemical synthesis. In this method the methanol is used as the esterification reaction of the raw material is used as a reaction solvent, in order to sodium methoxide or paratoluene sulfonic acid as catalyst, 3, 5 di-tert-butyl - 4 - hydroxy benzoic acid with methanol in order to 1.0: 2.0 - 1.0: 15.0 molar ratio, in the 60 - 80 °C reflow reaction for 8 - 14h after evaporate the solvent, solid first with sodium carbonate or sodium bicarbonate saturated solution washing, distilled water washing to neutral, filtering, drying, to get the pure product 3, 5 - di-tert-butyl - 4 - hydroxy-benzoic acid methyl ester compound. The process of the invention is simple, mild reaction conditions, which avoids the use of toxic solvents, the cost is reduced, while at the same time favorable to the environment; to obtain high yield, high purity, and has a good industrial application prospect. (by machine translation)

The occurrence of 3-oxo-6-keto-cyclohexa-1,4-diene (p-quinoketene) during an esterification process

We succeeded in demonstrating the occurrence of a 3-oxo-6-keto-cyclohexa-1,4-diene (also called p-quinoketene) 5 during an esterification process of a p-hydroxy acyl chloride with a hindered phenol, in the presence of triethylamine.