42224-52-2

Upstream product

• 28915-66-4 (E)-1-methoxy-2-(4-nitrostyryl)benzene 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 104-03-0 4-nitrobenzeneacetic acid 
• 100-14-1 4-nitrobenzyl chloride 
• 1530-42-3 (4-nitrobenzyl)triphenylphosphonium chloride 
• 90-02-8 salicylaldehyde 
• 2767-70-6 (p-nitrobenzyl)triphenylphosphonium bromide 

Downstream Products

• 321655-07-6 {2-[(E)-2-(4-Nitro-phenyl)-vinyl]-phenoxy}-acetic acid ethyl ester 
• 310422-87-8 (E)-4'-nitro-2-stilbenyloxyacetic acid hydrazide 

Relevant academic research and scientific papers

Preparation of (E)-2-Hxdroxy-4'-Substituted Stilbenes

Sixteen (E)-2-hydroxy-4'-substituted stilbenes have been prepared by the Wittig reaction.Direct coupling of the appropriate p-substituted benzylidenetriphenylphosphoranes with salicylaldehyde afforded the (E)-stilbenols (2) 4'-R = H(2a), Me(2b), But(2c), Ph(2d), CN(2e), NO2(2i), OMe(2k), F(2n), Cl(2o), and Br(2p).Alternatively, the Wittig reaction of o-methoxymethoxybenzylidenetriphenylphosphorane with various p-substituted benzaldehydes gave the (E)-methoxymethylstilbenols (4) which upon acidic cleavage furnished the corresponding stilbenols (2) 4'-R = CN(2e), CO2Me(2f), NMe2(2h), OH(2j), OAc(2m), and I(2q).The symmetrical (E)-2,2'-dihydroxystilbene was obtained in an analogous fashion.Reduction of nitrostilbenol (2i) yielded the corresponding aminostilbenol (2g).