422569-47-9Relevant academic research and scientific papers
An improved sonogashira coupling procedure for the construction of rigid aromatic multifunctional monomers bearing 1,3-substituted acetylenic units
Davidson, Louise,Freebairn, Keith W.,Russell, Andrew T.,Trivedi, Harish S.,Hayes, Wayne
, p. 251 - 254 (2002)
The efficient synthesis of rigid multifunctional vinylic monomers 1 and 2 from 3,5-dibromobenzene derivatives and propargyl alcohol via the Sonogashira reaction is reported. For example, a series of 3,5-bis(3-hydroxyprop-1-ynl)benzoate ester derivatives have been prepared efficiently using an improved palladium catalyst system. Subsequent hydrolysis and reaction with 4-vinylaniline afforded a new monomer 2 for use in functional macroporous polymer systems. In addition, Sonogashira and Wittig methodologies have been optimised in order to construct successfully an alternative rigid monomer 1 from 3,5-dibromobenzaldehyde.
Synthesis and evaluation of a solid supported molecular tweezer type receptor for cholesterol
Davidson, Louise,Blencowe, Anton,Drew, Michael G. B.,Freebairn, Keith W.,Hayes, Wayne
, p. 758 - 766 (2007/10/03)
A new macroporous stationary phase bearing 'tweezer' receptors that exhibit specificity for cholesterol has been constructed from rigid multifunctional vinylic monomers derived from 3,5-dibromobenzoic acid, propargyl alcohol and cholesterol. The synthesis
