618-58-6

Basic information

• Product Name: 3,5-Dibromobenzoic acid
• Synonyms: 3,5-dibromo-benzoicaci;Benzoic acid, 3,5-dibromo-;RARECHEM AL BO 0773;3,5-DIBROMOBENZOIC ACID;BUTTPARK 99\57-19;3,5-DibroMobenzoic Acid, 97+%
• CAS NO: 618-58-6
• Molecular Formula: C₇H₄Br₂O₂
• Molecular Weight: 279.91
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Acids & Esters;Bromine Compounds;Building Blocks for Dendrimers;Functional Materials;C7;Carbonyl Compounds;Carboxylic Acids;Benzoic acid series;OLED
• Mol File: 618-58-6.mol
• Article Data: 17

Chemical Properties

• Melting Point: 218-220 °C(lit.)
• Boiling Point: 355.2 °C at 760 mmHg
• Flash Point: 168.6 °C
• Appearance: white to light yellow crystal powder
• Density: 1.9661 (rough estimate)
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.4970 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Very faint turbidity in methanol.
• PKA: 3.42±0.10(Predicted)
• BRN: 1940691
• CAS DataBase Reference: 3,5-Dibromobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dibromobenzoic acid(618-58-6)
• EPA Substance Registry System: 3,5-Dibromobenzoic acid(618-58-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: DG6290010
• HazardClass: IRRITANT
• Hazardous Substances Data: 618-58-6(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powder

Uses

3,5-Dibromobenzoic acid may be used for the syntheses (+)-menthyl 3,5-dibromobenzoate, di-tert-butyl 4-[2-(tert-butoxycarbonyl)ethyl]-4-(3,5-dibromobenzamido)heptanedioate2, (L)-methyl 2-(3,5-dibromobenzamido)-3-phenylpropanoate.

General Description

3,5-Dibromobenzoic acid is 3,5-dibromo-substituted benzoic acid.

Synthesis

3,5-Dibromobenzoic acid was synthesized from anthranilic acid by bromination, diazotization and additional reactions derived. The bromination reaction is carried out at about 20°C. After the reaction, the crystals are filtered, washed with hot water to remove anthranilic acid and hydrochloric acid, and recrystallized with acetic acid to obtain o-amino-3,5-dibromobenzoic acid; then use sodium nitrite to carry out diazotization in hydrochloric acid at about 0°C, then add the diazonium salt into ethanol containing calcium sulfate at 60-70°C in batches. After the addition is complete, continue stirring for 10 minutes, filter to obtain the crude product, and recrystallize with ethanol to obtain the finished product.

InChI:InChI=1/C7H4Br2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H,10,11)/p-1

Upstream product

• 61858-41-1 2-amino-1-(4-iodophenyl)ethanone hydrochloride 
• 61858-39-7 2-AMINO-1-(3-BROMO-PHENYL)-ETHANONE HYDROCHLORIDE 
• 61858-38-6 2-BroMo-M-iodoacetophenone 
• 6185-83-7 N-(2,4-dimethylphenyl)-2-(trifluoromethyl)benzamide 
• 6185-82-6 N-(2,5-dimethylphenyl)-N~2~-(4-methoxyphenyl)-N~2~-[(4-methylphenyl)sulfonyl]glycinamide 
• 61857-87-2 pyridazino[4,5-b]quinoxalin-1(2H)-one 
• 61857-83-8 2,2-DIMETHYL-5-THIOPHEN-3-YL-[1,3]DIOXANE-4,6-DIONE 
• 6185-76-8 (4-Methoxyphenyl)(4-(trifluoroMethyl)phenyl)Methanone 
• 618-57-5 2-PROPYL SUCCINIC ACID 
• 61857-39-4 POLY-L-HISTIDINE 
• 61857-23-6 Ethanone, 1-[5-[(dimethylamino)methylene]-1,3-cyclopentadien-1-yl]- (9CI) 
• 61857-21-4 1,2-Dihydrodibenzo[a,e]cyclobuta[c]cyclooctene-1,2-dione 
• 61857-00-9 2-Pyrrolidinecarboxamide, 1-hydroxy-2-methyl- 
• 61856-99-3 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE 

Downstream Products

• 61858-84-2 Ethanone, 1-(3-ethyl-4-methyl-5-isoxazolyl)- (9CI) 
• 61859-84-5 methyl (2E)-3-pyridin-3-ylprop-2-enoate 
• 61859-96-9 Methyl 3-(trifluoroMethyl)-1H-pyrazole-4-carboxylate 
• 6186-04-5 diethyl [bis(phenylamino)methylidene]phosphoramidate 
• 61860-72-8 Cyclohexene, 1,2-dimethoxy- (9CI) 
• 6186-07-8 N-(2,4-dimethoxyphenyl)-N~2~-(4-methoxyphenyl)-N~2~-(methylsulfonyl)glycinamide 
• 61860-99-9 N-(Trimethylsilyl)-2,2-dimethylpropane-1-imine 
• 6186-10-3 1,3-bis[4-(benzyloxy)phenyl]urea 
• 618-61-1 3-METHYL-5-NITRO ANILINE 
• 6186-11-4 4-nitrophenyl [4-(benzyloxy)phenyl]carbamate 
• 6186-12-5 1-[4-(benzyloxy)phenyl]-3-butylurea 
• 61861-34-5 5(4H)-Isoxazolone,3-methyl-4-[(methylthio)methylene]-,(Z)-(9CI) 
• 61861-35-6 5(4H)-Isoxazolone,3-methyl-4-[(methylthio)methylene]-,(E)-(9CI) 
• 6186-13-6 N-(4-Hydroxyphenyl)carbamic acid 4-aminophenyl ester 

Recommend Products

• 51329-15-8  methyl 3,5-dibromobenzoate 
• 67-56-1  methanol 
• 109-72-8  n-butyllithium 
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• 676-58-4  methylmagnesium chloride 
• 123-72-8  butyraldehyde 
• 163625-26-1  2-isocyano-N-methoxy-N-methylacetamide 
• 6311-60-0  3,5-dibromonitrobenzene 
• 7697-37-2  nitric acid 
• 609-85-8  2-amino-3,5-dibromobenzoic acid 
• 65-85-0  benzoic acid 
• 185110-18-3  2-(1-benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone 
• 68858-20-8  Fmoc-Val-OH