42267-32-3

Upstream product

• 203873-67-0 (S)-methyl 2-(2-nitrophenylsulfonamido)-3-phenylpropanoate 
• 108-98-5 thiophenol 
• 283611-40-5 N-methyl-N-(o-nitrobenzenesulfonyl)-L-phenylalanine methyl ester 
• 931-59-9 benzenesulfenyl chloride 

Relevant academic research and scientific papers

Synthesis of N-methyl L-phenylalanine for total synthesis of pepticinnamin e

The target compounds 3, 10 and 11 were synthesized through different N-methylation strategies. The concise and efficient preparation of them in large scale was developed and 3, 10 and 11 were obtained in suitable form used for both nitrogen-end and oxygen-end extension in next coupling reaction in peptides synthesis, specifically in total synthesis of natural pepticinnamin E.