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9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine, also known as 2-chloro-2-deoxy-9-β-D-arabinofuranosyladenine or Cladribine, is a synthetic purine nucleoside analog with antiviral and immunosuppressive properties. It is primarily used in the treatment of hairy cell leukemia, a rare type of blood cancer, and other lymphoproliferative disorders. Cladribine works by inhibiting DNA synthesis and repair, leading to the death of rapidly dividing cells, such as cancer cells and immune cells. Its chemical structure consists of a 9-adenine base attached to a 2-chloro-2-deoxy-β-D-arabinofuranosyl sugar moiety, which allows it to be incorporated into DNA and disrupt its function. Due to its effectiveness in treating certain cancers and autoimmune diseases, Cladribine has become an important therapeutic agent in the field of oncology and immunology.

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  • 4227-33-2 Structure
  • Basic information

    1. Product Name: 9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine
    2. Synonyms:
    3. CAS NO:4227-33-2
    4. Molecular Formula:
    5. Molecular Weight: 285.69
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 4227-33-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine(4227-33-2)
    11. EPA Substance Registry System: 9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine(4227-33-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 4227-33-2(Hazardous Substances Data)

4227-33-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4227-33-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4227-33:
(6*4)+(5*2)+(4*2)+(3*7)+(2*3)+(1*3)=72
72 % 10 = 2
So 4227-33-2 is a valid CAS Registry Number.

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