42275-92-3

Usage

Uses

Used in Pharmaceutical Industry:
2-CHLORO-N-ISOPROPYLPROPANAMIDE is used as a chemical intermediate for the synthesis of various pharmaceutical products. Its role in this industry is crucial for the development of new drugs and medications, contributing to advancements in healthcare and medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CHLORO-N-ISOPROPYLPROPANAMIDE serves as an essential intermediate in the production of agrochemicals. It aids in the development of pesticides, herbicides, and other agricultural chemicals that are vital for enhancing crop protection and yield.
Used in Organic Compounds Production:
2-CHLORO-N-ISOPROPYLPROPANAMIDE is utilized as a building block in the synthesis of a wide range of organic compounds. Its versatility in chemical reactions allows for the creation of various compounds used in different industries, including plastics, dyes, and other specialty chemicals.
It is important to reiterate that due to the potential toxic and irritating effects of 2-CHLORO-N-ISOPROPYLPROPANAMIDE on the respiratory system and skin, strict safety measures should be adhered to during its handling and application in any industry.

InChI:InChI=1/C6H12ClNO/c1-4(2)8-6(9)5(3)7/h4-5H,1-3H3,(H,8,9)

Upstream product

• 7623-09-8 2-chloropropionyl chloride 
• 75-31-0 isopropylamine 

Downstream Products

• 162375-39-5 N-isopropyl-2-(phenylthio)propanamide 
• 162375-31-7 N-iso-propyl-Z-3-chloro-2-(phenylthio)propenamide 

Relevant academic research and scientific papers

Palladium-Catalyzed β-C(sp3)-H Arylation of Aliphatic Ketones Enabled by a Transient Directing Group

The direct arylation of aliphatic ketones has been developed via Pd-catalyzed β-C(sp3)-H bond functionalization with 2-(aminooxy)-N,N-dimethylacetamide as a novel transient directing group (TDG), which showed remarkable directing ability to generate arylated products in moderate to good yields. Furthermore, the reaction can tolerate abundant substrate of ketones and aryl iodides. This study expands the scope of applications for TDGs.

GLUCOSE UPTAKE INHIBITORS

Provided hererin are compounds that modulate glucose uptake activityand are useful for treating cancer, autoimmune diseases, inflammation, infectious diseases, and metabolic diseases. In certain embodiments, the compounds modulate glucose uptake activity by modulating cellular components, including, but not limited to those related to glycolysis and known transporters/co-transporters of glucose such as GLUT1 and other GLUT family members/alternative hexose transporters. In certain embodiments, the compounds have the structure of formula I: Formula (I) wherein the variables have the values disclosed herein.

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.