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2-Keto-3-deoxygluconate (KDG) is an important organic compound that plays a crucial role in the metabolism of glucose. It is an intermediate product in the pentose phosphate pathway, a metabolic pathway that generates NADPH and ribose-5-phosphate, which are essential for various cellular processes, including the synthesis of nucleotides and fatty acids. KDG is formed from glucose-6-phosphate through a series of enzymatic reactions, including the action of glucose-6-phosphate dehydrogenase and 6-phosphogluconolactonase. It is then further metabolized to ribulose-5-phosphate, which can enter the glycolytic pathway or be used for the synthesis of nucleotides. KDG is also involved in the detoxification of certain xenobiotics and plays a role in the regulation of cellular redox balance.

4229-39-4

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4229-39-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4229-39-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4229-39:
(6*4)+(5*2)+(4*2)+(3*9)+(2*3)+(1*9)=84
84 % 10 = 4
So 4229-39-4 is a valid CAS Registry Number.

4229-39-4Downstream Products

4229-39-4Relevant academic research and scientific papers

Pyruvate Aldolases as Reagents for Stereospecific Aldol Condensation

Allen, Sarah T.,Heintzelman, Geoffrey R.,Toone, Eric J.

, p. 426 - 427 (2007/10/02)

KDPG aldolase, a representative member of the largest but as of yet unexplored group of aldolases which utilize pyruvate as the nucleophilic component in aldol condensation, accepts a number of unnatural aldehydes as electrophiles in stereospecific aldol condensation, providing access to highly and differentially functionalized α-keto acid products.

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