42290-97-1

Usage

Uses

Used in Pharmaceutical Industry:
3-METHYL-1-PHENYL-BUTYLAMINE is used as a building block for the synthesis of various drugs and pharmaceutical products. Its unique structure allows it to be a key component in the development of new medications, contributing to the advancement of healthcare and treatment options.
Used in Organic Synthesis:
3-METHYL-1-PHENYL-BUTYLAMINE is utilized as a reagent in organic synthesis, enabling the creation of a wide range of chemical compounds. Its versatility in this field facilitates the production of various organic molecules for different applications.
Used in Chemical Research:
In the realm of chemical research, 3-METHYL-1-PHENYL-BUTYLAMINE serves as a valuable compound for studying the properties and reactions of amines. Its unique structure provides researchers with opportunities to explore new chemical pathways and mechanisms, furthering scientific understanding and innovation.
The exact properties and uses of 3-METHYL-1-PHENYL-BUTYLAMINE may vary depending on the specific application and the intended purpose of the compound, highlighting its adaptability and significance in diverse fields.

InChI:InChI=1/C11H17N/c1-9(2)8-11(12)10-6-4-3-5-7-10/h3-7,9,11H,8,12H2,1-2H3

Upstream product

• 582-62-7 3-methyl-1-phenylbutan-1-one 
• 100-47-0 benzonitrile 
• 100-42-5 styrene 

Downstream Products

• 102844-96-2 2-[(E)-3-Methyl-1-phenyl-butylimino]-1,2-diphenyl-ethanone 
• 102844-93-9 N-(1-phenyl-3-methylbutyl)-1,2-diphenyl-2-aminoethanol 
• 102844-93-9 (1R,2R)-2-((S)-3-Methyl-1-phenyl-butylamino)-1,2-diphenyl-ethanol 
• 32556-50-6 N-(1-Phenyl-3-methyl-butyl)-harnstoff 
• 80961-01-9 benzylidene-(3-methyl-1-phenyl-butyl)-amine 

Relevant academic research and scientific papers

Fe-Catalyzed radical-type difunctionalization of styrenes with aliphatic aldehydes and trimethylsilyl azide: Via a decarbonylative alkylation-azidation cascade

A convenient Fe-catalyzed decarbonylative alkylation-azidation cascade reaction of styrene derivatives with aliphatic aldehydes and TMSN3 to provide aliphatic azides is developed. With DTBP as an oxidant and radical initiator, this reaction smoothly converts aliphatic aldehydes into 1°, 2° and 3° alkyl radicals and subsequently allows for the cascade construction of C(sp3)-C(sp3) and C(sp3)-N bonds via radical insertion and nucleophilic azidation.

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: Discovery and exploration of the carboxyamide side chain

A series of 3-(2-aminocarbonyl-4-phenoxymethylphenyl)propanoic acid analogs were synthesized and evaluated for their EP3 antagonist activity in the presence of additive serum albumin. Several compounds were biologically evaluated for their in vivo efficacy with respect to the PGE2-induced uterine contraction in pregnant rats as well as their pharmacokinetics. The discovery process of these potent and selective EP3 antagonists and their structure activity relationship are also presented.

N-Tert-butyldimethylsilyl imines as intermediates for the synthesis of amines and ketones

Grignard reagents add to benzonitrile at low temperature catalyzed by CuBr and TBSCl affording N-TBS ketimines, which were investigated as intermediaries for the synthesis of primary amines and ketones. N- silylimines were easily obtained by an organolithium addition to benzonitrile followed by a reaction with TBSCl in CH2Cl2. In situ reduction of these imines by BH3 and 1,3,2-oxazaborolidines 1 or 2 as chiral templates afforded the corresponding amines with modest to good enantiomeric excess.