42290-97-1

Basic information

• Product Name: 3-METHYL-1-PHENYL-BUTYLAMINE
• Synonyms: 3-METHYL-1-PHENYL-BUTYLAMINE;(3-methyl-1-phenylbutyl)amine hydrochloride;MFCD09971356
• CAS NO: 42290-97-1
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.26
• Mol File: 42290-97-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 237.2°Cat760mmHg
• Flash Point: 99.5°C
• Appearance: /
• Density: 0.924g/cm³
• Vapor Pressure: 0.0455mmHg at 25°C
• Refractive Index: 1.514
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-METHYL-1-PHENYL-BUTYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-1-PHENYL-BUTYLAMINE(42290-97-1)
• EPA Substance Registry System: 3-METHYL-1-PHENYL-BUTYLAMINE(42290-97-1)

Safety Data

• Hazardous Substances Data: 42290-97-1(Hazardous Substances Data)

Usage

General Description

3-Methyl-1-phenyl-butylamine is a chemical compound that belongs to the class of amines. It is a tertiary amine with a branched alkyl chain and a phenyl group attached to the nitrogen atom. 3-METHYL-1-PHENYL-BUTYLAMINE is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical products. It may also have applications in the field of organic synthesis and chemical research. The exact properties and uses of 3-Methyl-1-phenyl-butylamine may vary depending on the specific application and the intended use of the compound.

InChI:InChI=1/C11H17N/c1-9(2)8-11(12)10-6-4-3-5-7-10/h3-7,9,11H,8,12H2,1-2H3

Upstream product

• 582-62-7 3-methyl-1-phenylbutan-1-one 
• 100-42-5 styrene 
• 100-47-0 benzonitrile 

Downstream Products

• 32556-50-6 N-(1-Phenyl-3-methyl-butyl)-harnstoff 
• 102844-96-2 2-[(E)-3-Methyl-1-phenyl-butylimino]-1,2-diphenyl-ethanone 
• 102844-93-9 N-(1-phenyl-3-methylbutyl)-1,2-diphenyl-2-aminoethanol 
• 102844-93-9 (1R,2R)-2-((S)-3-Methyl-1-phenyl-butylamino)-1,2-diphenyl-ethanol 
• 80961-01-9 benzylidene-(3-methyl-1-phenyl-butyl)-amine 

Relevant articles and documents

Fe-Catalyzed radical-type difunctionalization of styrenes with aliphatic aldehydes and trimethylsilyl azide: Via a decarbonylative alkylation-azidation cascade

A convenient Fe-catalyzed decarbonylative alkylation-azidation cascade reaction of styrene derivatives with aliphatic aldehydes and TMSN3 to provide aliphatic azides is developed. With DTBP as an oxidant and radical initiator, this reaction smoothly converts aliphatic aldehydes into 1°, 2° and 3° alkyl radicals and subsequently allows for the cascade construction of C(sp3)-C(sp3) and C(sp3)-N bonds via radical insertion and nucleophilic azidation.

N-Tert-butyldimethylsilyl imines as intermediates for the synthesis of amines and ketones

Grignard reagents add to benzonitrile at low temperature catalyzed by CuBr and TBSCl affording N-TBS ketimines, which were investigated as intermediaries for the synthesis of primary amines and ketones. N- silylimines were easily obtained by an organolithium addition to benzonitrile followed by a reaction with TBSCl in CH2Cl2. In situ reduction of these imines by BH3 and 1,3,2-oxazaborolidines 1 or 2 as chiral templates afforded the corresponding amines with modest to good enantiomeric excess.