42292-42-2

Usage

Uses

1-Demethyltriazolam is an impurity of Triazolam (T767380), a sedative, hypnotic.

Upstream product

• 110-85-0 piperazine 
• 71368-68-8 1-bromo-8-chloro-6-(2-chlorophenyl)-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 109-01-3 1-methyl-piperazine 
• 13484-38-3 1-(2-ethoxyethyl)piperazine 
• 56764-71-7 1-(2-methylythioethyl)piperazine 
• 88708-40-1 1-(3-methoxypropyl)piperazine 

Downstream Products

• 37115-38-1 [8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-1-ylmethyl]-dimethyl-amine 
• 88701-80-8 8-chloro-6-(2-chlorophenyl)-1-<4-(2-phenylthioethyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-78-4 8-chloro-6-(2-chlorophenyl)-1-<4-(2-phenoxyethyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-71-7 8-chloro-6-(2-chlorophenyl)-1-<4-(3-methoxypropyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-73-9 8-chloro-6-(2-chlorophenyl)-1-<4-(2-ethoxyethyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-75-1 8-chloro-6-(2-chlorophenyl)-1-<4-(2-methylthioethyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-69-3 8-chloro-6-(2-chlorophenyl)-1-<4-(2-methoxyethyl)piperazino>-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 88701-77-3 8-chloro-6-(2-chlorophenyl)-1-piperazino-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 71368-76-8 8-chloro-6-(2-chlorophenyl)-1-(4-methylpiperazino)-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 
• 71368-68-8 1-bromo-8-chloro-6-(2-chlorophenyl)-4H-s-triazolo<4,3-a>-1,4-benzodiazepine 

Relevant academic research and scientific papers

Methods for the production of 4H-s-triazolo[4,3-a][1,4]benzodiazepine 5N-oxides

The title compounds are prepared by reacting a 3-amino-3,4-dihydro-4-hydroxy-4-phenylquinazoline with a reactive derivative of a halogenoacetic acid, reacting the resultant halogenoacetyl derivative with a weak acid, reacting the resultant 2-(3-halomethyl-s-triazol-4-yl)benzophenone with hydroxylamine and subjecting the resultant 2-(3-hydroxyamino-methyl-s-triazol-4-yl)benzophenone to dehydration to effect ring closure.