42297-40-5 Usage
General Description
1,3,7-trimethyl-8-nitro-3,7-dihydro-1H-purine-2,6-dione, also known as caffeine, is a natural stimulant found in coffee, tea, and various other beverages and foods. It belongs to the group of xanthine alkaloids and is chemically classified as a methylxanthine. Caffeine works by blocking the action of adenosine, a neurotransmitter that relaxes the brain and makes you feel drowsy. This results in increased alertness and a temporary reduction in feelings of fatigue. Caffeine is commonly used to improve mental alertness, enhance physical performance, and alleviate fatigue. However, excessive consumption of caffeine can lead to adverse effects such as anxiety, insomnia, and rapid heart rate.
Check Digit Verification of cas no
The CAS Registry Mumber 42297-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,2,9 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 42297-40:
(7*4)+(6*2)+(5*2)+(4*9)+(3*7)+(2*4)+(1*0)=115
115 % 10 = 5
So 42297-40-5 is a valid CAS Registry Number.
42297-40-5Relevant articles and documents
Purines. XIV [1]. Synthesis and properties of 8-nitroxanthine and its N- methyl derivatives
Mosselhi,Pfleiderer
, p. 1221 - 1228 (2007/10/02)
Xanthine (1) and its N-methyl derivatives 2-16 have been nitrated to the corresponding 8-nitro derivatives 17-32 under different reaction conditions. Nitration in glacial acetic acid with nitric acid works well with the N-7 unsubstituted and some of the 9-methylxanthines, respectively, whereas the 7- methylxanthine derivatives react best with nitronium tetrafluoroborate in sulfolane or glacial acetic acid. The 8-nitro group can be displaced nucleophilically to form 8-chloro-, 33, 34, 8-ethoxy-, 35, 36, and uric acid derivatives 37-40, respectively. The newly synthesized 8-nitroxanthines have been characterized by elemental analyses, pK-determinations and uv and 1H- nmr spectra.
Murexide reaction of caffeine using nitric acid
Kozuka,Koyama,Okitsu
, p. 941 - 945 (2007/10/02)
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