4230-25-5Relevant academic research and scientific papers
Synthesis, biological activity, and SAR of antimycobacterial 9-aryl-, 9-arylsulfonyl-, and 9-benzyl-6-(2-furyl)purines
Bakkestuen, Anne Kristin,Gundersen, Lise-Lotte,Utenova, Bibigul T.
, p. 2710 - 2723 (2007/10/03)
9-Aryl-, 9-arylsulfonyl- and 9-benzyl-6-(2-furyl)purines were synthesized by N-alkylation or N-arylation of the purine followed by Stille coupling to introduce the furyl substituent in the 6-position and the compounds screened for activity against Mycobac
Purine N-alkylated derivatives. SRN1 synthesis and functional group transformations
Gharbaoui, Tawfik,Benhida, Rachid,Chastanet, Jacqueline,Lechevallier, Andre,Maillos, Philippe,Beugelmans, Rene
, p. 561 - 574 (2007/10/02)
Purine and its 6-chloro, 6-methoxy, 6-amino and 2-amino-6-chloro derivatives are efficient nucleophiyles in SRN1 reactions with various functionalized gem halo-nitroalkanes as substrates in which good regioselectivity on N9 is observ
