423151-49-9Relevant academic research and scientific papers
Selected michael additions to thiophene-containing analogues of chalcone
Roman, Gheorghe
, p. 751 - 760 (2015/11/24)
Using thiophene-containing analogues of chalcone as substrates, a series of Michael additions were investigated. Thia-Michael addition of 4-chlorothiophenol led to 1-(substituted aryl)-3-(4-chlorophenylmercapto)-1-(2-thienyl)-1-propanones, whereas catalyt
Vanillin-derived antiproliferative compounds influence Plk1 activity
Carrasco-Gomez, Roberto,Keppner-Witter, Sarah,Hieke, Martina,Lange, Lisa,Schneider, Gisbert,Schubert-Zsilavecz, Manfred,Proschak, Ewgenij,Sp?nkuch, Birgit
supporting information, p. 5063 - 5069 (2014/12/11)
We synthesized a series of vanillin-derived compounds and analyzed them in HeLa cells for their effects on the proliferation of cancer cells. The molecules are derivatives of the lead compound SBE13, a potent inhibitor of the inactive conformation of huma
Regioselective protection of the 4-hydroxyl of 3,4-dihydroxy-benzaldehyde
Plourde, Guy L.,Spaetzel, Randy R.
, p. 697 - 705 (2007/10/03)
The regioselective protection of the 4-hydroxyl group of 3,4-dihydroxy-benzaldehyde was accomplished with seven different protecting groups (benzyl, p-methoxybenzyl, o-nitrobenzyl, 2,6-dichlorobenzyl, 3,4-dichlorobenzyl, vinyl and propargyl) in yields ranging between 67-75percent.
