423169-68-0 Usage
Uses
Used in Pharmaceutical Industry:
SC 57461A is used as a potent and selective inhibitor of LTA4 hydrolase for its potential therapeutic applications in treating conditions related to the arachidonic acid cascade, such as inflammation and allergy.
Used in Research Applications:
SC 57461A is used as a research tool to study the role of LTA4 hydrolase in various biological processes and to investigate the effects of inhibiting this enzyme on different cellular pathways and functions.
Used in Drug Development:
SC 57461A is used in the development of new drugs targeting LTA4 hydrolase, which may have potential applications in treating various diseases and conditions related to the arachidonic acid cascade.
Used in Inflammation and Allergy Treatment:
SC 57461A is used as an inhibitor of LTA4 hydrolase to block the production of LTB4, a potent inflammatory mediator, and potentially provide relief from inflammation and allergy symptoms.
Used in Preclinical Models:
SC 57461A is used in preclinical models, such as rat models of ionophore-induced peritoneal eicosanoid production and mice ear edema models, to study its effects on eicosanoid biosynthesis and inflammation.
Biological Activity
Potent and selective inhibitor of LTA 4 hydrolase. Does not inhibit other enzymes of the arachidonic acid cascade including COX-1, COX-2, LTC 4 synthase and 5-lipoxygenase. Potently inhibits LTB 4 production in whole blood (IC 50 = 49 nM). Orally active.
Check Digit Verification of cas no
The CAS Registry Mumber 423169-68-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,3,1,6 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 423169-68:
(8*4)+(7*2)+(6*3)+(5*1)+(4*6)+(3*9)+(2*6)+(1*8)=140
140 % 10 = 0
So 423169-68-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H25NO3/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17/h2-4,6-11H,5,12-16H2,1H3,(H,22,23)
