423178-18-1Relevant articles and documents
Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase
Tang, Jing,Vernekar, Sanjeev Kumar V.,Chen, Yue-Lei,Miller, Lena,Huber, Andrew D.,Myshakina, Nataliya,Sarafianos, Stefan G.,Parniak, Michael A.,Wang, Zhengqiang
, p. 85 - 96 (2017/04/06)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encoded enzymatic function not clinically validated as an antiviral target. 2-Hydroxyisoquinoline-1,3-dione (HID) is known to confer
NOVEL INHIBITORS OF FLAVIVIRUS REPLICATION
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Page/Page column 134, (2010/06/15)
The present invention relates to a series of novel compounds, methods to prevent or treat viral infections by using the novel compounds, processes for preparation of the compounds, their use to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Hepatitis C virus (HCV). The present invention also relates to the novel compounds for use as a medicine, more preferably for use as a medicine for the prevention or treatment of viral infections, preferably infections with viruses belonging to the family of the Flaviviridae.
Aqueous organotin chemistry: Part 3 - Triphenyltin hydride and di-n-butyltin dichloride mediated nucleophilic substitution of 2-iodobenzoates in water
Sarma,Maitra
, p. 1148 - 1150 (2007/10/03)
This paper demonstrates the nucleophilic displacement of the iodine in 2-iodobenzoates mediated by triphenyltin hydride and di-n-butyltin dichloride in water.