42333-78-8Relevant articles and documents
Mechanochemical Release of Non-Covalently Bound Guests from a Polymer-Decorated Supramolecular Cage
G?stl, Robert,Küng, Robin,Pausch, Tobias,Rasch, Dustin,Schmidt, Bernd M.
, p. 13626 - 13630 (2021)
Supramolecular coordination cages show a wide range of useful properties including, but not limited to, complex molecular machine-like operations, confined space catalysis, and rich host–guest chemistries. Here we report the uptake and release of non-covalently encapsulated, pharmaceutically-active cargo from an octahedral Pd cage bearing polymer chains on each vertex. Six poly(ethylene glycol)-decorated bipyridine ligands are used to assemble an octahedral PdII6(TPT)4 cage. The supramolecular container encapsulates progesterone and ibuprofen within its hydrophobic nanocavity and is activated by shear force produced by ultrasonication in aqueous solution entailing complete cargo release upon rupture, as shown by NMR and GPC analyses.
Supramolecular networks derived from hexacyanoferrates and nitrogen heterocyclic cations
Xydias, Pantelis,Lymperopoulou, Smaragda,Dokorou, Vasiliki,Manos, Manolis,Plakatouras, John C.
, p. 341 - 357 (2019)
Eight novel supramolecular frameworks (bpyH2)2[Fe(CN)6]·2H2O (1), (bpyH2)(H3O)[Fe(CN)6] (2), (bpeH2)(H3O)[Fe(CN)5(CNH)]·H2O (3), (bpeH2)(H5O2)[Fe(CN)6]·2H2O (4), (dabcoH2)(H3O)[Fe(CN)6]·2H2O (5), (ampyH2)2[Fe(CN)6]·2H2O (6), (tptzH3)2[Fe(CN)4(CNH)2]3·10H2O (7), and (tptzH3)[Fe(CN)6]·3H2O (8) (where bpy = 4,4′-bipyridine, bpe = 1,2-bis(4-pyridyl)ethylene, dabco = 1,4-diazabicyclo[2.2.2]octane, ampy = 4-aminomethylpyridine, tptz = tris(4-pyridyl)triazine) have been synthesized by the reaction of the nitrogen heterocycle with ferrocyanide or ferricyanide salts, under mild conditions. The supramolecular structures are constructed mainly by cooperative hydrogen bonding between the inorganic anions, the organic cations and oxoniums or lattice water molecules. There are some characteristic features that can separate the compounds in groups. Those are (a) increase of H-bonding ability by formation of supramolecular complexes, (b) formation of hydro- and dihydro-hexacyanoferrates and (c) the participation of the cationic heterocycle as constituent of the structure or as a guest. The structures are additionally discussed in terms of topology.
Mixed-matrix materials using metal-organic polyhedra with enhanced compatibility for membrane gas separation
Fulong, Cressa Ria P.,Liu, Junyi,Pastore, Vincent J.,Lin, Haiqing,Cook, Timothy R.
supporting information, p. 7905 - 7915 (2018/06/29)
Discrete metal-organic polyhedra (MOPs) containing copper(ii), palladium(ii), and iron(ii) nodes were synthesized as fillers for mixed-matrix materials (MMMs) with a polyvinylidine fluoride (PVDF) polymer phase and contrasted against an MMM containing a metal-organic framework, MOF-5. When a given MOP was soluble in the precursor solutions, the resulting MMMs were thin, flexible, and homogeneous based on microscopy and SEM imaging. Analogous MMM formation using either insoluble MOPs or the inherent insoluble MOF-5 showed a higher degree of phase separation and inhomogeneity. Even when a MOP was not fully soluble, a significant particle size decrease was observed in contrast to the MOF-5 materials wherein the crystallites remained largely intact. This is a consequence of solubilizing the MOP fillers into the polymer solvent. The crystallinity and thermal stabilities of the MMMs were compared to pure PVDF using powder X-ray diffraction, and differential scanning calorimetry, indicating that the incorporation of MOPs both decreased overall crystallinity as well as increased thermal stability. In addition, MMMs containing PdMOP and FeMOP showed improved gas permeabilities relative to pure PVDF for H2, N2, CH4, and CO2, with the 10 wt% FeMOP membrane more selective for CO2 over N2 and H2.