42361-45-5

Usage

Uses

2-Furancarboxamide, N-methoxy-(9CI) may have potential use in pharmaceutical and medicinal chemistry due to its structural characteristics and properties as a carboxamide derivative. However, further research and studies are needed to fully understand and explore the potential applications and effects of 2-Furancarboxamide, N-methoxy-(9CI).

Upstream product

• 88-14-2 2-furanoic acid 
• 527-69-5 2-furancarbonyl chloride 
• 593-56-6 N-methoxylamine hydrochloride 

Downstream Products

• 1364511-73-8 6-methoxy-4,5-diphenylfurano[2,3-c]pyridin-7(6H)-one 
• 1402345-52-1 N-methoxy-N-phenylfuran-2-carboxamide 
• 611-13-2 2-furoic acid methyl ester 
• 88-14-2 2-furanoic acid 
• 17357-60-7 p-tolyl furan-2-carboxylate 

Relevant academic research and scientific papers

Pd(II)-Catalyzed asymmetric oxidative annulation of N-alkoxyheteroaryl amides and 1,3-dienes

The first Pd(II)-catalyzed asymmetric oxidative annulation of N-alkoxyaryl amides and 1,3-dienes is reported, which features particular applicability for quick assembly of different types of chiral heterocycles with high yields and enantioselectivities. A novel chiral pyridine-oxazoline bearing a methoxyl group at the C-5 position and a gem-dimethyl group on the oxazoline moiety was found to be crucial for conversion.

Palladium-Nanoparticles-Catalyzed Oxidative Annulation of Benzamides with Alkynes for the Synthesis of Isoquinolones

A novel method to synthesize isoquinolones via oxidative annulation of N-alkoxy benzamides and alkynes using binaphthyl-stabilized palladium nanoparticles (Pd-BNP) as catalyst has been developed. This methodology affords various isoquinolone derivatives in good to excellent yields with high regioselectivities in the presence of air as oxidant. N-Methoxybenzothioamide was also found to undergo oxidative annulation with alkyne successfully and provided a sulfur analogue of isoquinolones in moderate yields. The Pd-BNP catalyst was easily recovered and reused up to four times without any apparent agglomeration. (Figure presented.).

Copper-catalyzed C-N bond formation through C-H/N-H activation: A novel approach to the synthesis of multisubstituted ureas

A copper-catalyzed cross-dehydrogenative coupling reaction that involves C-H activation of formamides and N-H activation of N-alkoxy amides has been developed. This protocol affords a novel approach to the synthesis of multisubstituted ureas under mild co

Pd-catalysed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation

An atom economical synthesis of isoquinolinones and analogues via ligand-free Pd-catalysed C-H and N-H double activation has been developed. A series of isoquinolinones were obtained in good to excellent yields. Good regioselectivities were also observed during the activation reactions with unsymmetrical alkynes. A practical one-pot procedure for the preparation of N-H isoquinolinones is also described. The Royal Society of Chemistry 2012.

Copper-catalyzed cross-coupling of O -alkyl hydroxamates with aryl iodides

N-Aryl-O-alkylhydroxamic acid derivatives were prepared by copper-catalyzed cross-coupling of hydroxamates with aryl iodides. The reaction conditions are compatible with standard hydroxy-protecting groups on the hydroxylamine moiety and are applicable to