42366-51-8

Basic information

• Product Name: Phosphine oxide, cyclohexylmethylphenyl-
• CAS NO: 42366-51-8
• Molecular Formula: C13H19OP
• Molecular Weight: 222.267
• Mol File: 42366-51-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 386.5±15.0 °C(Predicted)
• Density: 1.04±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Phosphine oxide, cyclohexylmethylphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, cyclohexylmethylphenyl-(42366-51-8)
• EPA Substance Registry System: Phosphine oxide, cyclohexylmethylphenyl-(42366-51-8)

Safety Data

• Hazardous Substances Data: 42366-51-8(Hazardous Substances Data)

Upstream product

• 172487-18-2 ethyl Phenylphosphinate 
• 108-85-0 1-bromocyclohexane 
• 7301-81-7 methyl-phenyl-phosphinic acid ethyl ester 
• 2946-61-4 phenylphosphonous acid dimethyl ester 
• 70530-88-0 Chlor-diethylamino-cyclohexyl-phosphan 
• 409325-44-6 Methyl-cyclohexyl-phosphinsaeure-methylester 

Downstream Products

• 21232-93-9 (R_P*)-cyclohexyl(methyl)phenylphosphine oxide 
• 37775-94-3 (-)-(S_P)-Cyclohexylmethylphenylphosphine oxide 
• 1354631-44-9 (+/-)-cyclohexylmethylphenylphosphine borane 
• 1354049-91-4 C₁₃H₁₉ClP⁽¹⁺⁾*Cl^(1-) 

Relevant articles and documents

A facile and practical preparation ofP-chiral phosphine oxides

A practical and cost-effective synthetic method ofP-chiral diarylalkyl, aryldialkyl, and triaryl phosphine oxides by using readily available chiral diphenyl-2-pyrrolidinemethanol as the auxiliary is developed. The long-standing racemization issue during s

Raney-Ni reduction of phosphine sulfides

A variety of tertiary phosphine sulfides have been reduced by Raney-Ni to give the corresponding phosphineswith high efficiency and undermild conditions. Alkyl, aryl, acyclic, cyclic, aswell as sterically crowded phosphine sulfides are reduced with equal facility. Optically active P-stereogenic phosphine sulfides are reduced stereospecifically with clean retention of configuration at P. Reductions of unsaturated phosphinesulfides is not fully chemoselective and takes place with concomitant partial reduction of the double bond. Clean reduction of the unsaturated phosphine sulfides to the corresponding fully saturated phosphines can be achieved in one step by running the reduction under H2atmosphere (balloon).