423761-65-3Relevant academic research and scientific papers
A study of base-catalyzed aldol reaction of trimethylsilyl enolates
Sutar,Joshi
, p. 1553 - 1560 (2015/02/02)
Mukaiyama-type aldol reaction of trimethylsilyl enolates with aldehydes in the presence of a base is a complicated reaction. It usually results in various products determined by the nature of base and reaction medium. The present study has been undertaken to understand these factors and design new Lewis base catalysts to optimize the yield of desired aldol product. It has been shown that mild Bronsted base with inbuilt hydrogen bonding sites are efficient catalysts for the reactions involving trimethylsilyl enolates. Based on the observed results, a mechanism is proposed to explain the reaction outcome.
Iron(II)-catalyzed asymmetric hydrosilylation of acetophenone
Flueckiger, Michelle,Togni, Antonio
experimental part, p. 4353 - 4360 (2011/10/08)
Four new ligands containing a pentasubstituted cyclopentadiene tethered to a stereogenic diamine unit have been prepared and used in the iron-catalyzed enantioselective hydrosilylation of acetophenone. Catalytically active species have been generated in s
