42389-54-8

Basic information

• Product Name: N,N-DIETHYL-CYCLOHEXANE-1,4-DIAMINE
• Synonyms: N,N-DIETHYL-CYCLOHEXANE-1,4-DIAMINE;N1,N1-DIETHYLCYCLOHEXANE-1,4-DIAMINE;N,N-Diethyl-1,4-cyclohexanediaMine (cis- and trans- Mixture);trans-N,N-Diethyl-cyclohexane-1,4-diamine;N,N-Diethyl-1,4-cyclohexanediamine;N,N-Diethyl-1,4-cyclohexanediamine (cis- and trans- mixture)
• CAS NO: 42389-54-8
• Molecular Formula: C₁₀H₂₂N₂
• Molecular Weight: 170.3
• Mol File: 42389-54-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 111°C(lit.)
• Flash Point: 85.2°C
• Appearance: /
• Density: 0.91g/cm³
• Vapor Pressure: 0.118mmHg at 25°C
• Refractive Index: 1.4740 to 1.4780
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: N,N-DIETHYL-CYCLOHEXANE-1,4-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIETHYL-CYCLOHEXANE-1,4-DIAMINE(42389-54-8)
• EPA Substance Registry System: N,N-DIETHYL-CYCLOHEXANE-1,4-DIAMINE(42389-54-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 2735 8/PG III
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 42389-54-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1296, 1946 DOI: 10.1021/ja01211a053

InChI:InChI=1/C10H22N2/c1-3-12(4-2)10-7-5-9(11)6-8-10/h9-10H,3-8,11H2,1-2H3

Upstream product

• 2216-15-1 1-diethylamino-4-nitrobenzene 
• 120-22-9 N,N-diethyl-4-nitrosoaniline 
• 93-05-0 N,N-diethylaniline 
• 2615-25-0 trans-1,4-cyclohexyldiamine 
• 177906-48-8 trans-N-Boc-1,4-cyclohexanediamine 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 101592-73-8 N-cyclohexyl-N'-(4-diethylamino-cyclohexyl)-thiourea 
• 102165-75-3 2-acetoxy-benzoic acid-(4-diethylamino-cyclohexylamide) 
• 76004-34-7 N'-(2-chloro-4-quinazolinyl)-N,N-diethyl-1,4-cyclohexanediamine hydrochloride 
• 144128-43-8 7-Chloro-3-(3,4-dichloro-phenyl)-1-[(E)-4-diethylamino-cyclohexylimino]-10-hydroxy-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 76004-42-7 N-(2,6-Dichloro-quinazolin-4-yl)-N',N'-diethyl-cyclohexane-1,4-diamine; hydrochloride 
• 47083-68-1 1-cyclohexyl-3-(4-diethyl-aminocyclohexyl)carbodiimide 
• 76004-94-9 6-Chloro-N²-(3,4-dichloro-phenyl)-N⁴-(4-diethylamino-cyclohexyl)-quinazoline-2,4-diamine; hydrochloride 
• 76004-59-6 N²-(3,4-Dichloro-phenyl)-N⁴-(4-diethylamino-cyclohexyl)-quinazoline-2,4-diamine; hydrochloride 
• 76004-61-0 N²-(3,5-dichlorophenyl)-N⁴-<4-(diethylamino)cyclohexyl>-2,4-quinazolinediamine dihydrochloride 
• 76004-63-2 N²-(3,5-Dibromo-phenyl)-N⁴-(4-diethylamino-cyclohexyl)-quinazoline-2,4-diamine; hydrochloride 
• 76005-27-1 N²-(4-Diethylamino-cyclohexyl)-N⁴-(4-trifluoromethyl-phenyl)-quinazoline-2,4-diamine; hydrochloride 
• 76005-23-7 N⁴-(3,4-Dichloro-phenyl)-N²-(4-diethylamino-cyclohexyl)-quinazoline-2,4-diamine; hydrochloride 
• 76005-24-8 N⁴-(3,5-Dichloro-phenyl)-N²-(4-diethylamino-cyclohexyl)-quinazoline-2,4-diamine; hydrochloride 

Relevant articles and documents

Novel isoxazole carboxamides as growth hormone secretagogue receptor (GHS-R) antagonists

Novel isoxazole carboxamides have been identified as growth hormone secretagogue receptor (GHS-R) antagonists. Substituent modification off the 5-position of the isoxazole ring led to analogues with potent binding affinity and functional antagonism of GHS-R. A potent analogue (32) with high aqueous solubility and good GPCR selectivity was also identified as a potential pharmacological tool for in vivo studies.