42393-12-4

Upstream product

• 67-56-1 methanol 

Downstream Products

• 1217974-48-5 C₂₀H₁₅Cl₂NO₄ 
• 1257520-16-3 (4R,4aS,7aS)-methyl 4-(2,4-dichlorophenyl)-4,4a,5,7a-tetrahydrocyclopenta[b]pyran-2-carboxylate 
• 1201664-57-4 (+)-4-(1H-indol-3-yl)-2-oxo-4-(2,4-dichlorophenyl)butyric acid methyl ester 
• 1228393-37-0 trimethyl 2-(2,4-dichlorophenyl)-4-oxobutane-1,1,4-tricarboxylate 
• 1171110-68-1 (S)-methyl 6-amino-5-cyano-4-(2,4-dichlorophenyl)-4H-pyran-2-carboxylate 

Relevant academic research and scientific papers

Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330: Effect of substrate structure and mechanism

Candida parapsilosis ATCC 7330 was found to be an efficient biocatalyst for the deracemisation of aryl α-hydroxy esters (65-85% yield and 90-99% ee). A variety of aryl and aryl substituted α-hydroxy esters were synthesized to reflect steric and electronic effects on biocatalytic deracemisation. The mechanism of this biocatalytic deracemisation was found to be stereoinversion.