42393-13-5

Basic information

• Product Name: Methyl-3,4-dichlorbenzylidenpyruvat
• Synonyms: Methyl-3,4-dichlorbenzylidenpyruvat
• CAS NO: 42393-13-5
• Molecular Weight: 259.089
• Mol File: 42393-13-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methyl-3,4-dichlorbenzylidenpyruvat(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-3,4-dichlorbenzylidenpyruvat(42393-13-5)
• EPA Substance Registry System: Methyl-3,4-dichlorbenzylidenpyruvat(42393-13-5)

Safety Data

• Hazardous Substances Data: 42393-13-5(Hazardous Substances Data)

Upstream product

• 6287-38-3 3,4-dichlorobenzaldehyde 
• 1558055-79-0 C₁₂H₁₂Cl₂O₄ 
• 67-56-1 methanol 

Downstream Products

• 1321818-82-9 C₂₀H₁₇Cl₂NO₃ 
• 1321818-58-9 C₂₀H₁₇Cl₂NO₃ 
• 1558055-59-6 C₁₁H₉Cl₂NO₃ 
• 1558055-69-8 methyl 5-(3,4-dichlorophenyl)-4,5-dihydroisoxazole-3-carboxylate 
• 1210055-03-0 C₁₉H₁₅Cl₂NO₃ 

Relevant articles and documents

Asymmetric Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters: Allylboration/Oxy-Cope Rearrangement

A highly enantioselective formal conjugate allyl addition of allylboronic acids to β,γ-unsaturated α-ketoesters has been realized by employing a chiral NiII/N,N′-dioxide complex as the catalyst. This transformation proceeds by an allylboration/oxy-Cope rearrangement sequence, providing a facile and rapid route to γ-allyl-α-ketoesters with moderate to good yields (65–92 %) and excellent ee values (90–99 % ee). The isolation of 1,2-allylboration products provided insight into the mechanism of the subsequent oxy-Cope rearrangement reaction: substrate-induced chiral transfer and a chiral Lewis acid accelerated process. Based on the experimental investigations and DFT calculations, a rare boatlike transition-state model is proposed as the origin of high chirality transfer during the oxy-Cope rearrangement.