42445-18-1

Upstream product

• 100-52-7 benzaldehyde 
• 3446-89-7 4-(Methylthio)benzaldehyde 

Downstream Products

• 53458-17-6 1,2-bis(4-methylsulfanyl-phenyl)ethane-1,2-dione 
• 13205-48-6 4-(methylthio)benzoic acid 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 66659-98-1 4,5-bis<4-(methylthio)phenyl>-1H-imidazole-2-thiol 
• 97059-75-1 5,6-Bis-(4-methanesulfinyl-phenyl)-2,3-dihydro-imidazo[2,1-b]thiazole 1-oxide 
• 66660-06-8 4,5-Bis-(4-methanesulfinyl-phenyl)-1,3-dihydro-imidazole-2-thione 
• 66660-07-9 5,6-bis(4-(methylsulfinyl)phenyl)-2,3-dihydroimidazo<2,1-b>thiazole 
• 78631-70-6 5,6-bis-(4-methylsulfanyl-phenyl)-2,3-dihydro-imidazo[2,1-b]thiazole 
• 66659-98-1 4,5-Bis-(4-methylsulfanyl-phenyl)-1,3-dihydro-imidazole-2-thione 
• 66660-05-7 4,4'-bis(methylsulfinyl)benzoin 
• 143546-98-9 (3-{2-[4,5-Bis-(4-methylsulfanyl-phenyl)-oxazol-2-yl]-ethyl}-phenoxy)-acetic acid methyl ester 

Relevant academic research and scientific papers

Compound, Photopolymerization Initiator Containing Said Compound, and Photosensitive Resin Composition Containing Said Photopolymerization Initiator

This compound, which absorbs long-wavelength active energy rays and generates with high-efficiency radicals and strong bases, and which has excellent reaction efficiency in a base generating chain reaction, is represented by formula (1), where, in formula

PHOTOSENSITIVE RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND PRINTED WIRING BOARD

An objective of the present invention is to provide a photosensitive resin composition having excellent insulation reliability. As a solution, the present invention provides a photosensitive resin composition containing: (A) a photobase generator containi

Compound, Photopolymerization Initiator Containing Said Compound, and Photosensitive Resin Composition Containing Said Photopolymerization Initiator

This compound which has excellent solvent solubility and compatibility with a resin, and which can generate bases and radicals with high efficiency by being irradiated with active energy rays, is represented by formula (1), where, in formula (1), R1

NEW COMPOUND, ACTIVE ENERGY RAY POLYMERIZATION INITIATOR CONTAINING THAT COMPOUND, AND ACTIVE ENERGY RAY CURABLE COMPOSITION CONTAINING THAT POLYMERIZATION INITIATOR

PROBLEM TO BE SOLVED: To provide a new compound which in combination with an active energy ray polymerizable compound can form a composition excellent in storage stability, where a cured product of the composition can be used as an active energy ray polym

NOVEL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID COMPOUND, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR

The purpose of the present invention is to provide: a novel compound which can generate a base and radical upon the irradiation with an active energy ray; a photopolymerization initiator which comprises the novel compound; and a photosensitive resin composition which contains the photopolymerization initiator, has high sensitivity and excellent storage stability, and can be formed into a cured article that does not have a metal-corrosive property. The novel compound is represented by formula (1): (wherein R1 to R6 independently represent a hydrogen atom, a hydroxy group, an alkoxy group, an organic group other than the aforementioned substituents, or the like; X represents a residue having a structure such that n hydrogen atoms are removed from a saturated hydrocarbon containing a ring structure; and n represents an integer of 1 to 6).

2, 3-Diaryl-5-ethylsulfanylmethyltetrahydrofurans as a new class of COX-2 inhibitors and cytotoxic agents

2,3-Diaryl-5-ethylsulfanylmethyltetrahydrofuran-3-ols were designed and synthesized by the allylations of benzoins followed by iodocyclization and nucleophilic replacement reactions with ethanthiol. These molecules exhibit IC50 for COX-2 at 50 over all the 59 human tumor cell lines at μ M concentration. The Royal Society of Chemistry.

Competition between α-cleavage and energy transfer in α-azidoacetophenones

(Chemical Equation Presented) Molecular modeling demonstrates that the first excited state of the triplet ketone (T1K) in azide 1b has a (π,π*) configuration with an energy that is 66 kcal/mol above its ground state and its second excited state (T2K) is 10 kcal/mol higher in energy and has a (n,π*) configuration. In comparison, T 1K and T2K of azide 1a are almost degenerate at 74 and 77 kcal/mol above the ground state with a (n,π*) and (π,π*) configuration, respectively. Laser flash photolysis (308 nm) of azide 1b in methanol yields a transient absorption (λmax = 450 nm) due to formation of T1K, which decays with a rate of 2.1 × 10 -5 s-1 to form triplet alkylnitrene 2b (λmax = 320 nm). The lifetime of nitrene 2b was measured to be 16 ms. In contrast, laser flash photolysis (308 nm) of azide 1a produced transient absorption spectra due to formation of nitrene 2a (λ max = 320 nm) and benzoyl radical 3a (λmax = 370 nm). The decay of 3a is 2 × 10-5 s-1 in methanol, whereas nitrene 2a decays with a rate of ～91 s-1. Thus, T 1K (π,π*) in azide 1b leads to energy transfer to form nitrene 2b; however, α-cleavage is not observed since the energy of T 2K (n,π*) is 10 kcal/mol higher in energy than T 1K, and therefore, T2K is not populated. In azide 1a both α-cleavage and energy transfer are observed from T1K (n,π*) and T2K (π,π*), respectively, since these triplet states are almost degenerate. Photolysis of azide 1a yields mainly product 4, which must arise from recombination of benzoyl radicals 3a with nitrenes 2a. However, products studies for azide 1b also yield 4b as the major product, even though laser flash photolysis of azide 1b does not indicate formation of benzoyl radical 3b. Thus, we hypothesize that benzoyl radicals 3 can also be formed from nitrenes 2. More specifically, nitrene 2 does undergo α-photocleavage to form benzoyl radicals and iminyl radicals. The secondary photolysis of nitrenes 2 is further supported with molecular modeling and product studies.

Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles

A number of trisubstituted imidazoles were made and several found to be potent antiinflammatory agents when examined in the carrageenan rat paw edema test. The antiinflammatory activity of these compounds is retained in adrenalectomized rats. Unlike many previously reported antiinflammatory agents, these compounds are extremely weak acids pK[a] ≥ 11) and are therefore not ionized at physiological pH. One compound, 4,5 bis (4 methoxyphenyl) 2 trifluoromethylimidazole (flumizole), is more potent than indometacin in the rat paw edema test and, in contrast to some related compounds, does not cause photosensitization in mice.