42449-79-6Relevant academic research and scientific papers
Regioselective synthesis of heterospirocyclic isobenzofuranones and medium-sized lactones by multiple anion capture reactions of 1,3-dianions
Langer, Peter,Doering, Manfred,Goerls, Helmar
, p. 1511 - 1517 (2001)
The multicomponent reaction of 1,3-dianions with ketones and oxalic acid dichloride or diethylmalonic dichloride afforded six- to eight-membered lactones. Treatment of the dianion of 3-acetylindole with benzophenone and diethylmalonic dichloride resulted in the formation of a cyclic 1,3,5-triketooctene. The reaction of 1,3-dianions with ketones and phthalic dichloride resulted in the formation of heterospirocyclic isobenzofuranones rather than of medium-sized rings.
Synthesis of medium-sized rings, spiro-annulated oxazacycles and 1- amino-3-siloxy dienes based on regioselective reactions of ambident dianions
Langer, Peter,D?ring, Manfred,Seyferth, Dietmar
, p. 135 - 137 (1999)
Ambident dianions react as dinucleophiles with various electrophiles to form six- to nine-membered heterocycles, spirocyclic compounds and 1-amino- 3-siloxy dienes.
