4246-84-8Relevant academic research and scientific papers
Regioselective synthesis of rac-(1R,4R,6R,6aR)-6′-phenyl-7′, 8′-dihydro-1″H,2′H,6′H-dispiro[cycloalkane-1, 5′-pyrrolo[1,2-c][1,3]thiazole-4′,3″-indole]-2, 2″-diones through 3 + 2 cycloaddition reaction
Poornachandran, Mahalingam,Jayagobi, Mathesan,Raghunathan, Raghavachary
, p. 240 - 243 (2009)
Synthesis of a series of novel rac-(1R,4R,6R,6aR)-6′-phenyl-7′, 8′-dihydro-1″H,2′H,6′H-dispiro[cycloalkane-1, 5′-pyrrolo[1,2-c][1,3]thiazole-4′,3″-indole]-2, 2″-diones by cycloaddition reaction is described. The nonstabilised azomethine ylide generated by the reaction of isatin and thiazolidine-2- carboxylic acid has been regioselectively trapped by various substituted benzylidene cycloalkanones.
Regioselective synthesis of dispirocycloalkanooxindolopyrrolidines and dispirocyclalkanoindanopyrrolidines
Poornachandran, Mahalingam,Jayagobi, Mathesan,Raghunathan, Raghavachary
body text, p. 551 - 563 (2010/04/06)
Synthesis of a series of novel dispirocycloalkanone-oxindolopyrrolidines and dispirocycloalkanone-indanopyrrolidines is described. The nonstabilized azomethine ylides generated from a secondary amino acid, sarcosine, and carbonyl components (isatin and ninhydrin) have been effectively trapped by the dipolarophiles, arylidene cycloalkanones, to afford dispiropyrrolidines. The one-pot azomethine ylide cycloaddition reactions were highly regioselective. Copyright Taylor & Francis Group, LLC.
Three-component reaction of cycloheptanone, 6-amino-1,3-dimethyluracil and aromatic aldehydes; x-ray structure, and anti-inflammatory evaluation of the products
Hegab, Mohamed I.,Hassan, Nasser A.,Abdel-Megeid, Farouk M. E.
scheme or table, p. 1117 - 1126 (2009/05/30)
1,3-Dimethyl-5-aryl-1,6,7,8,9,10-hexahydrocyclohepta[5,6]pyrido[2,3-d] pyrimidine-2,4-diones 4a, b (the linear regioisomers) and the Schiff bases, 6-N-benzylidenamino-1,3-dimethyluracil derivatives 5a, b, were isolated from a three-component reaction of c
