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42466-69-3

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42466-69-3 Usage

General Description

(Z)-ethyl 2-cyano-3-ethoxyacrylate is a chemical compound with the molecular formula C9H11NO3. It is commonly used as a monomer in the synthesis of polymers and as a building block in organic synthesis. (Z)-ethyl 2-cyano-3-ethoxyacrylate is a clear, colorless liquid with a characteristic odor. It is insoluble in water but soluble in organic solvents. (Z)-ethyl 2-cyano-3-ethoxyacrylate is also known for its potential applications in the pharmaceutical and agrochemical industries. Additionally, it is important to handle this compound with care and follow safety protocols due to its potential health hazards and flammability.

Check Digit Verification of cas no

The CAS Registry Mumber 42466-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,4,6 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 42466-69:
(7*4)+(6*2)+(5*4)+(4*6)+(3*6)+(2*6)+(1*9)=123
123 % 10 = 3
So 42466-69-3 is a valid CAS Registry Number.

42466-69-3Relevant articles and documents

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Ioffe,S.T. et al.

, (1970)

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Preparation method of ethoxymethylene ethyl cyanoacetate

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Paragraph 0018-0020, (2020/12/30)

The invention discloses a preparation method of ethoxymethylene ethyl cyanoacetate. The method comprises the following steps: 1) adding triethyl orthoformate, ethyl cyanoacetate and acetic acid into areaction kettle, heating to 120-125 DEG C, evaporating out ethanol at the temperature, controlling the distillation speed, and distilling for 1 hour to obtain 15-20 L of ethanol; 2) titrating aceticacid into the reaction kettle, and carrying out reflux distillation on ethanol until no ethanol is distilled; 3) carrying out reduced pressure distillation to collect triethyl orthoformate to obtain an ethoxymethylene ethyl cyanoacetate crude product; and 4) carrying out vacuum distillation on the crude product to obtain the ethoxymethylene cyanoethyl acetate. According to the invention, no solvent is used in the reaction process of preparing the target product, only a small amount of acetic acid is used as the catalyst, and the target product can be obtained with high yield; and the preparation method disclosed by the invention is short in period and relatively low in cost, and the recycled triethyl orthoformate can be used as a reactant to be reused.

SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS NADPH OXIDASE INHIBITORS

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Page/Page column 78-79, (2018/12/03)

The present application relates to substituted fused heteroaryl and heterocyclic compounds, useful as nicotinamide adenine dinucleotide phosphate oxidase inhibitors (NADPH oxidase inhibitors), processes for their preparation, pharmaceutical compositions comprising the compounds, and the use of the compounds or the compositions in the treatment or prevention of various diseases, conditions and/or disorders mediated by NADPH oxidase. (Formula I)

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