42468-42-8Relevant articles and documents
Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
Wilson, Kenneth J.,Xiao, Jingbo,Chen, Catherine Z.,Huang, Zaohua,Agoulnik, Irina U.,Ferrer, Marc,Southall, Noel,Hu, Xin,Zheng, Wei,Xu, Xin,Wang, Amy,Myhr, Courtney,Barnaeva, Elena,George, Emmett R.,Agoulnik, Alexander I.,Marugan, Juan J.
, p. 79 - 92 (2018/07/06)
A dose responsive quantitative high throughput screen (qHTS) of >350,000 compounds against a human relaxin/insulin-like family peptide receptor (RXFP1) transfected HEK293 cell line identified 2-acetamido-N-phenylbenzamides 1 and 3 with modest agonist acti