42468-43-9Relevant academic research and scientific papers
Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
Wilson, Kenneth J.,Xiao, Jingbo,Chen, Catherine Z.,Huang, Zaohua,Agoulnik, Irina U.,Ferrer, Marc,Southall, Noel,Hu, Xin,Zheng, Wei,Xu, Xin,Wang, Amy,Myhr, Courtney,Barnaeva, Elena,George, Emmett R.,Agoulnik, Alexander I.,Marugan, Juan J.
, p. 79 - 92 (2018)
A dose responsive quantitative high throughput screen (qHTS) of >350,000 compounds against a human relaxin/insulin-like family peptide receptor (RXFP1) transfected HEK293 cell line identified 2-acetamido-N-phenylbenzamides 1 and 3 with modest agonist acti
MODULATORS OF THE RELAXIN RECEPTOR 1
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Paragraph 0271-0272, (2015/05/05)
Disclosed are modulators of the human relaxin receptor 1, for example, of formula (I), wherein A, R1, and R2 are as defined herein, that are useful in treating mammalian relaxin receptor 1 mediated facets of human health, e.g., cardi
