424792-59-6

Basic information

• Product Name: methyl 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetate
• Synonyms: methyl 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetate
• CAS NO: 424792-59-6
• Molecular Weight: 246.306
• Mol File: 424792-59-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetate(424792-59-6)
• EPA Substance Registry System: methyl 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetate(424792-59-6)

Safety Data

• Hazardous Substances Data: 424792-59-6(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 110-83-8 cyclohexene 

Downstream Products

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 4335-77-7 cyclohexylmandelic acid 
• 10399-13-0 methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate 
• 424792-60-9 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetic acid 

Relevant articles and documents

Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof

The present invention relates to production of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid useful as an intermediate for pharmaceutical products, by an industrial means, economically, safely in a good yield. Novel 2-(2′-cyclohexen-1′-yl)-2-hydroxy-2-phenylacetic acid ester obtained by reacting cyclohexene and benzoylformic acid ester in the presence of a Lewis acid is hydrolyzed and reduced to give 2-cyclohexyl-2-hydroxy-2-phenylacetic acid.