424829-90-3 Usage
Uses
Used in Alzheimer's Disease Research:
FP-TZTP is used as an M2 selective muscarinic agonist for noninvasive studies of Alzheimer's disease with PET imaging. This allows researchers to gain insights into the progression of the disease and evaluate the effectiveness of potential treatments without the need for invasive procedures.
Check Digit Verification of cas no
The CAS Registry Mumber 424829-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,4,8,2 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 424829-90:
(8*4)+(7*2)+(6*4)+(5*8)+(4*2)+(3*9)+(2*9)+(1*0)=163
163 % 10 = 3
So 424829-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H16FN3S2/c1-15-6-2-4-9(8-15)10-11(14-17-13-10)16-7-3-5-12/h4H,2-3,5-8H2,1H3
424829-90-3Relevant academic research and scientific papers
Towards the development of new subtype-specific muscarinic receptor radiopharmaceuticals - Radiosynthesis and ex vivo biodistribution of [ 18F]3-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethylthio)-1,2, 5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyrid
Van Oosten, Erik M.,Wilson, Alan A.,Mamo, David C.,Pollock, Bruce G.,Mulsant, Benoit H.,Houle, Sylvain,Vasdev, Neil
experimental part, p. 1222 - 1232 (2011/02/24)
Muscarinic receptors have been implicated in neurological disorders including Alzheimer's disease, Parkinson's disease, and schizophrenia. Nineteen derivatives of thiadiazolyltetrahydropyridine (TZTP), a core that has previously shown high affinities towa