42510-95-2

Basic information

• Product Name: 1-((rel-1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-urea
• CAS NO: 42510-95-2
• Molecular Weight: 208.26
• Mol File: 42510-95-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-((rel-1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((rel-1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-urea(42510-95-2)
• EPA Substance Registry System: 1-((rel-1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-1-methyl-urea(42510-95-2)

Safety Data

• Hazardous Substances Data: 42510-95-2(Hazardous Substances Data)

Upstream product

• 590-28-3 potassium cyanate 
• 90-82-4 rac-pseudoephedrine 
• 134-71-4 rac-ephedrine hydrochloride 

Downstream Products

• 6317-31-3 trans-3,4-dimethyl-5-phenyloxazolidin-2-one 
• 2007-94-5 3,4r-dimethyl-5t-phenyl-oxazolidin-2-ylideneamine 
• 2007-94-5 (4R or 4S)-3,4r-dimethyl-5t-phenyl-oxazolidin-2-ylideneamine 

Relevant articles and documents

1,3-Heterazolidines-2-heterounsaturated compounds derived from ephedrines

Herein, a direct and easy method for preparing 2-oxo-, 2-thione- or 2-imine-1,3-heterazolidines derived from ephedrines and norephedrines are reported. The method is based on solvent free heating of ephedrines with oxocyanate or thiocyanate salts (180-200 °C). In the reactions with potassium oxocyanate in refluxing ethanol, it was possible to isolate ureidic derivatives. The structure and stereochemistry of the compounds were determined by 1H, 13C NMR, IR spectroscopies and mass spectrometry. Ureidic derivatives, cis-1,5-dimethyl-4-phenyl-imidazolidine-2-thione and trans-4-methyl-5-phenyl-thiazolidine-2-one are new compounds. Ephedrineurea, cis-1,5-dimethyl-4-phenyl-imidazolidine-2-thione and trans-4-methyl-5-phenyl-thiazolidine-2-one were also studied by X-ray diffraction.